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Effect of Citrus aurantium l. essential oil on muscle regeneration in mdx mice
(Soc Chilena Anatomia, 2011-01-01)
Duchenne muscular dystrophy (DMD) is a severe X-linked recessive disorder characterized by the progressive loss of muscular strength. Mdx mutant mice show a marked deficiency in dystrophin, which was related to muscle ...
INCREASED EXPRESSION of ACETYLCHOLINE RECEPTORS in the DIAPHRAGM MUSCLE of MDX MICE
(Wiley-Blackwell, 2008-12-01)
The absence of dystrophin in Duchenne muscular dystrophy (DMD) and in the mutant mdx mouse causes muscle degeneration and disruption of the neuromuscular junction. Based on evidence from the denervation-like properties of ...
Hormonal Receptors in Skeletal Muscles of Dystrophic Mdx Mice
(Hindawi Publishing Corporation, 2013-01-01)
Introduction. Several evidences show that muscles have an endocrine function. Glucocorticoid, estrogen, progesterone, and testosterone receptors have already been found in normal skeletal muscles, but not in dystrophic ...
Quantitative changes of nicotinic receptors in the hippocampus of dystrophin-deficient mice
(Elsevier B.V., 2012-11-05)
Lack of dystrophin in Duchenne muscle dystrophy (DMD) and in the mutant mdx mouse results in progressive muscle degeneration, structural changes at the neuromuscular junction, and destabilization of the nicotinic acetylcholine ...
Loss of neuronal projections in the dystrophin-deficient mdx mouse is not progressive
(Elsevier B.V., 2008-08-11)
Lack of dystrophin is known to reduce several cerebral fiber systems. To investigate if the loss of fibers is progressive, we analyzed projections of the trigeminal sensory system to the red nucleus in 3, 6, and 12 month ...
EPA protects against muscle damage in the mdx mouse model of Duchenne muscular dystrophy by promoting a shift from the M1 to M2 macrophage phenotype
(2013-10-01)
In dystrophic mdx mice and in Duchenne muscular dystrophy, inflammation contributes to myonecrosis. Previously, we demonstrated that eicosapentaenoic acid (EPA) decreased inflammation and necrosis in dystrophic muscle. In ...
Erythropoietin reduces the expression of myostatin in mdx dystrophic mice
(Assoc Bras Divulg Cientifica, 2014-11-01)
Erythropoietin (EPO) has been well characterized as a renal glycoprotein hormone regulating red blood cell production by inhibiting apoptosis of erythrocyte progenitors in hematopoietic tissues. EPO exerts regulatory effects ...
Intestine of dystrophic mice presents enhanced contractile resistance to stretching despite morphological impairment
(Amer Physiological Soc, 2014-02-01)
Protein dystrophin is a component of the dystrophin-associated protein complex, which links the contractile machinery to the plasma membrane and to the extra-cellular matrix. Its absence leads to a condition known as ...