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Gene structure and splicing in schistosomes
(ElsevierAmsterdam, 2011-08)
Schistosomes are blood dwelling platyhelminths with a complex life cycle and persist in the definitive host during decades, indicating that they are very successful parasites. The challenge of infecting two hosts from ...
Exploring the Schistosoma mansoni adult male transcriptome using RNA-seq
(ACADEMIC PRESS INC ELSEVIER SCIENCESAN DIEGO, 2012)
Schistosoma mansoni is one of the agents of schistosomiasis, a chronic and debilitating disease. Here we, present a transcriptome-wide characterization of adult S. mansoni males by high-throughput RNA-sequencing. We obtained ...
Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts
(COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, 2010)
Schistosoma mansoni is a well-adapted blood-dwelling parasitic helminth, persisting for decades in its human host despite being continually exposed to potential immune attack. Here, we describe in detail micro-exon genes ...
Folding factors and partners for the intrinsically disordered protein micro-exon gene 14 (MEG-14)
(Cell PressSaint Louis, 2013-06)
The micro-exon genes (MEG) of Schistosoma mansoni, a parasite responsible for the second most widely spread tropical disease, code for small secreted proteins with sequences unique to the Schistosoma genera. Bioinformatics ...
Microdissecção e captura a laser na investigação do gene TP53 em tecidos incluídos em parafina
(2007-02-01)
Background: Laser-capture micro-dissection (LCM) is a recently developed procedure that provides single cells or specific cell groups for molecular analysis. Currently, there are few LCM systems in Brazil, in such a way ...
Microdissecção e captura a laser na investigação do gene TP53 em tecidos incluídos em parafina
(Sociedade Brasileira de Patologia ClínicaSociedade Brasileira de PatologiaSociedade Brasileira de Citopatologia, 2007-02-01)
INTRODUÇÃO: Microdissecção e captura a laser (MCL) é uma técnica de desenvolvimento recente que permite a coleta de células individuais ou pequeno conjunto de células para análise molecular. Atualmente, no Brasil, há raros ...
Refinement of chromosome 3p22.3 region and identification of a susceptibility gene for bipolar affective disorder
(Wiley-blackwellHobokenEUA, 2013)
MicroRNAs involved in the HMGA2 deregulation and its co-occurrence with MED12 mutation in uterine leiomyoma
(2018-11-01)
STUDY QUESTION Can the mediator complex subunit 12 (MED12) mutation and high mobility group AT-hook 2 (HMGA2) overexpression co-occurrence be explained by the alternative mechanism of HMGA2 dysregulation in uterine leiomyomas ...
COL1A1 and miR-29b show lower expression levels during osteoblast differentiation of bone marrow stromal cells from Osteogenesis Imperfecta patients
(BioMed Central, 2014-04-27)
Abstract
Background
The majority of Osteogenesis Imperfecta (OI) cases are caused by mutations in one of the two genes, COL1A1 and COL1A2 encoding for the two chains that ...