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Molecular mechanisms underlying glutamatergic dysfunction in schizophrenia: Therapeutic implications
(2009)
Early models for the etiology of schizophrenia focused on dopamine neurotransmission because of the powerful anti-psychotic action of dopamine antagonists. Nevertheless, recent evidence increasingly supports a primarily ...
NNZ-2566, a Novel Analog of (1–3) IGF-1, as a Potential Therapeutic Agent for Fragile X Syndrome
(Springer, 2015)
Fragile X syndrome (FXS) is the most common
form of inherited intellectual disability. Previous studies
have implicated mGlu5 in the pathogenesis of the disease,
and many agents that target the underlying pathophysiology
of ...