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High-yield extraction of periplasmic asparaginase produced by recombinant Pichia pastoris harbouring the Saccharomyces cerevisiae ASP3 gene

Ferrara, Maria Antonieta; Severino, Neuza M. Bonomo; Valente, Richard H.; Perales, Jonas; Bon, Elba P. S. (Elsevier, 2018)

Purificação e caracterização de asparaginase II de Saccharomyces cerevisiae clonada em Pichia pastoris: estudo de um possível fármaco antileucêmico

Girão, Luciana Facchinetti de Castro; Rocha, Surza Lucia Gonçalves da; Teixeira, Ricardo Sobral; Ferrara, Maria Antonieta; Perales, Jonas; Bon, Elba Pinto da Silva (Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)

Production and Characterization of L-Asparaginases of Streptomyces Isolated from the Arauca Riverbank (Colombia)

Autor desconocido (The Open Microbiology Journal, 2019-01-19)

Introduction: L-asparaginase, is known as an anti-cancer agent, mainly used in acute lymphoblastic leukemia, which prevents the proliferation of tumor cells. This study shows that there are unexplored regions in Colombia ...

Polypeptide with Asparaginase Activity, Expression Cassette, Expression Vector, Host Cell, Pharmaceutical Composition, Methods for Producing a Polypeptide with Asparaginase Activity and for Preventing or Treating Cancer, and Use of a Polypeptide

Souza, Tatiana de Arruda Campos Brasil de; Zanchin, Nilson Ivo Tonin; Morais, Stephanie Bath de (United States Patent and Trademark Office, 2021)

Polypeptide with asparaginase activity, expression cassette, expression vector, host cell, pharmaceutical composition, methods for producing a polypeptide with asparaginase activity and for preventing or treating cancer, and use of a polypeptidePolypeptid mit asparaginase-aktivität, expressionskassette, expressionsvektor, wirtszelle, pharmazeutische zusammensetzung, verfahren zur herstellung eines polypeptids mit asparaginase-aktivität und zur vorbeugung oder behandlung von krebs sowie verwendung eines polypeptids

Souza, Tatiana de Arruda Campos Brasil de; Zanchin, Nilson Ivo Tonin; Morais, Stephanie Bath de (European Patent Office, 2021)

Optimization of L-asparaginase activity of Actinobacteria isolated from Guaviare river sediments in Colombia

Autor desconocido (Tropical Journal of Pharmaceutical Research, 2019-03-16)

Purpose: To optimize the L-asparaginase activity of Actinobacteria isolated from Guaviare river sediments in Colombia. Methods: Actinobacterial strains were evaluated for their L-asparaginase activity using phenol red ...

Genetic algorithm for deimmunization of Escherichia coli L-asparaginase

Trevizani, Raphael (Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2019)

Cenário brasileiro e mundial do biofármaco L-asparaginase

Borges, Mariana P.; Brum, Ricardo C.; Freire, Diana P. B. (Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)

Human L-asparaginase engineering for improvement of catalytic activity and application in Acute Lymphoblastic Leukemia therapy

Pinheiro, Maisa Pessoa; Guimarães, Ana Virgínia Frota; Furtado, Gilvan Pessoa; Lourenzoni, Marcos Roberto (Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2022)

Production of L-asparaginase by Filamentous Fungi

Sarquis, Maria Inez de Moura; Oliveira, Edna Maria Morais; Santos, Alberdan Silva; Costa, Gisela Lara da (Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)

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