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Differences in both inositol 1,4,5-triphosphate mass and inositol 1,4,5- triphosphate receptors between normal and dystrophic between normal and dystrophic skeletal muscle cell lines
(1998)
Human normal (RCMH) and Duchenne muscular dystrophy (RCD) cell lines, as well as newly developed normal and dystrophic murine cell lines, were used for the study of both changes in inositol 1,4,5-trisphosphate (IP3) mass ...
MTOR-independent autophagy induced by interrupted endoplasmic reticulum-mitochondrial Ca2+ communication: a dead end in cancer cells
(Taylor and Francis Inc., 2019)
© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. The interruption of endoplasmic reticulum (ER)-mitochondrial Ca2+ communication induces a bioenergetic crisis characterized by an increase of MTOR-independent ...
IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice
(Elsevier B.V., 2018)
© 2018 Duchenne muscular dystrophy (DMD) is characterized by a severe and progressive destruction of muscle fibers associated with altered Ca2+ homeostasis. We have previously shown that the IP3 receptor (IP3R) plays a ...
An Inositol 1,4,5-Triphosphate (IP3)-IP3 Receptor Pathway Is Required for Insulin-Stimulated Glucose Transporter 4 Translocation and Glucose Uptake in Cardiomyocytes
(ENDOCRINE SOC, 2010-10)
Intracellular calcium levels ([Ca2+](i)) and glucose uptake are central to cardiomyocyte physiology, yet connections between them have not been studied. We investigated whether insulin regulates [Ca2+](i) in cultured ...
Cyclic AMP cascade mediates the inhibitory odor response of isolated toad olfactory receptor neurons
(AMER PHYSIOLOGICAL, 2005-09)
Odor stimulation may excite or inhibit olfactory receptor neurons (ORNs). It is well established that the excitatory response involves a cyclic AMP (cAMP) transduction mechanism that activates a nonselective cationic cyclic ...
Calcium signaling in insulin action on striated muscle
(Churchill Livingstone, 2014)
© 2014 Elsevier Ltd. Striated muscles (skeletal and cardiac) are major physiological targets of insulin and this hormone triggers complex signaling pathways regulating cell growth and energy metabolism. Insulin increases ...
IGF-1 Induces IP3-Dependent Calcium Signal Involved in the Regulation of Myostatin Gene Expression Mediated by NFAT During Myoblast Differentiation
(Wiley Periodicals, 2013)
Skeletal muscle differentiation is a complex and highly regulated process characterized by cell cycle arrest, which is associated with
morphological changes including myoblast alignment, elongation, and fusion into ...
Trastornos plaquetarios primarios en la especie humana: Aspectos biomédicos: biología, patobiología y bioclínica
(Sociedad de Cirugía de Bogotá, Hospital de San José y Fundación Universitaria de Ciencias de la Salud, 2007-09-01)