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The Unsolved Jigsaw Puzzle of the Immune Response in Chagas Disease
(Frontiers Research Foundation, 2018-07)
Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune response in a very complex and flowery manner. The history of host-parasite co-evolution has provided this protozoan with means ...
Probiotics and trained immunity
(MDPI AG, 2021-09-14)
The characteristics of innate immunity have recently been investigated in depth in several research articles, and original findings suggest that innate immunity also has a memory capacity, which has been named “trained ...
Redirection of the immune response to the functional catalytic domain of cruzipain improves protective immunity against Trypanosoma cruzi infection
(Oxford University Press, 2010-12)
Despite the strong immune responses elicited after natural infection with Trypanosoma cruzi or vaccination against it, parasite survival suggests that these responses are insufficient or inherently inadequate. T. cruzi ...
Nanoparticles and immune cells
(Bentham Science Publishers, 2019-09)
Nanoparticles have gained ground in several fields. However, it is important to consider their potentially hazardous effects on humans, flora, and fauna. Human exposure to nanomaterials can occur unintentionally in daily ...
Recent advances in non-specific immune memory against bovine tuberculosis
(Elsevier, 2021-04)
Bovine tuberculosis is an important worldwide disease mainly related to cattle, although it also affects other mammals, including humans. In recent years, there have been considerable advances in the knowledge of the immune ...
Glycobiology of immune responses
(John Wiley & Sons Inc, 2012-04-23)
Unlike their protein roommates and their nucleic acid cousins, carbohydrates remain an enigmatic arm of biology. The central reason for the difficulty in fully understanding how carbohydrate structure and biological function ...
Bacterial glycans and their interactions with lectins in the innate immune system
(Journal of the Serbian Chemical Society, 2019-11)
Bacterial surfaces are rich in glycoconjugates that are mainly present in their outer layers and are of great importance for their interaction with the host innate immune system. The innate immune system is the first barrier ...
Changes in the TCRβ repertoire and tumor immune signature from a cutaneous melanoma patient immunized with the CSF-470 vaccine: A case report
(Frontiers Media S.A., 2018-05)
The allogeneic therapeutic vaccine CSF-470 has demonstrated a significant benefit over medium-dose IFNa2b in the distant metastasis-free survival for stages IIB-IIC-III cutaneous melanoma patients in a randomized phase ...
Histamine in cancer immunology and immunotherapy. Current status and new perspectives
(John Wiley & Sons Inc., 2021-10)
Cancer is the second leading cause of death globally and its incidence and mortality are rapidly increasing worldwide. The dynamic interaction of immune cells and tumor cells determines the clinical outcome of cancer. ...