In the last twenty' five years the knowledge of the part played by the hypophysis in carbohydrate metabolism has passed through two stages. In the first, from JL 1908 to 1929, all of the actions were attributed to the ...

The role of the anterior portion of the hypophysis in the production or intensification of diabetes was discovered in this Institute in 1929 and 1930 and since then has been studied continuously. An abstract of this work ...

Our investigations (1924-1930) have shown us that the pituitary gland is one of the most important endocrine factors in the regulation of carbohydrate metabolism. This fact had remained unknown up to the present, but the ...

The hypophysis influences biological functions in mammals at various levels, and its volumetric variation in Chiroptera is recently well known. We explored the relation of the hypophysis size as a whole (Hyp) and its ...

Orexins and their receptors OX1 and OX2 regulate energy balance and the sleep-wake cycle. We studied the expression of prepro-orexin (PPO), OX1, and OX2 in brain and pituitary under the influence of the hormonal status in ...

In the normal or diabetic condition the liver plays a fundamental homeostatic role, since it is the organ that produces glucose and thus governs the blood sugar level (28). The glucose output from the liver is increased ...

The action of the hypophysis on the pancreas has been demonstrated by a number of direct and indirect proofs. The latter, first reported from this Institute, are as follows: (a) Complete kypophysectomy or anterior (distal) ...