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Chronic hepatitis C: Hepatic fibrosis evolution after ineffective specific treatment
(H G E UPDATE MEDICAL PUBLISHING S A, 2008)
Background/Aims: Specific treatment of chronic hepatitis C is effective in 50% of patients, improving the]liver`s fibrosis, necroinflammatory changes and steatosis. However, in patients still viremic after treatment the ...
Platelet-derived growth factor A mRNA in platelets is associated with the degree of hepatic fibrosis in chronic hepatitis C
(Soc Brasileira Medicina Tropical, 2017-01-01)
Introduction: Transforming growth factor beta 1 (TGFB1) and platelet-derived growth factor (PDGF) are the main cytokines related to hepatic fibrogenesis. Methods: RNA isolated from the platelets and hepatic tissue of 43 ...
Nuevos tratamientos para la infección por virus de hepatitis C y el proceso de fibrosis hepática
(Sociedad Médica de Santiago, 2009)
Phase angle is associated with advanced fibrosis in patients chronically infected with hepatitis C virus
(2016-06-01)
Aims The objective of this study was to evaluate the association of phase angle (PhA) with advanced liver fibrosis in patients chronically infected with hepatitis C virus (HCV). Main methods One hundred sixty consecutive ...
Human Platelet Antigen Genotype Is Associated With Progression of Fibrosis in Chronic Hepatitis C
(Wiley-Blackwell, 2012-01-01)
Although progression of fibrosis in the chronic hepatitis C depends on environmental, viral, and host factors, genetic polymorphisms have been associated recently with this progression, including the expression of integrins, ...
Interferon lambda 4 rs12979860 C>T polymorphism is not associated with liver fibrosis in patients with hepatitis C El polimorfismo rs12979860 C>T en el gen Interferón lambda 4 no está asociado a riesgo de fibrosis hepática en pacientes chilenos con hepati
(Sociedad Medica de Santiago, 2018)
© 2018, Sociedad Medica de Santiago. All rights reserved. Background. Host genetic predispositions may be important determinants of liver fibrosis in patients with chronic hepatitis C (CHC). The association between ...
Progression of liver fibrosis in blood donors infected with hepatitis C virus
(2004-12-01)
Background/Aims. Chronic hepatitis by HCV is progressive towards cirrhosis, with variable rate. We evaluated the rate of fibrosis progression (RFP), risk factors associated with advanced fibrosis (F3 and F4), and estimated ...
The modulatory effect of triclosan on the reversion of the activated phenotype of LX-2 hepatic stellate cells
(Wiley-Blackwell, 2019-11-12)
Hepatic diseases leading to fibrosis affect millions of individuals worldwide and are a major public health challenge. Although, there have been many advances in understanding hepatic fibrogenesis, an effective therapy ...
Histological response study of chronic viral hepatitis C patients treated with interferon alone or combined with ribavirin
(Brazilian Society of Infectious Diseases, 2008)
Chronic hepatitis C is often a progressive, fibrotic disease that can lead to cirrhosis and other complications. The recommended therapy is a combination of interferon and ribavirin. Besides its antiviral action, interferon ...