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Plant-based vaccine for livestock : key points to unleash platform translation in developing countries
(2016-12)
Ten years ago the first plant-based vaccine was licensed (DowAgrosciences). It was only 20 years after the first report of a recombinant protein obtained through plant transformation technology. Back then, this vaccine was ...
Genetically attenuated Trypanosoma cruzi parasites as a potential vaccination tool
(Taylor & Francis, 2012-06-18)
Chagas disease is the clinical manifestation of the infection produced by the parasite Trypanosoma cruzi. Currently there is no vaccine to prevent this disease and the protection attained with vaccines containing non-replicating ...
Efficacy of a high quality O1/Campos foot-and-mouth disease vaccine upon challenge with a heterologous Korean O Mya98 lineage virus in pigs
(Elsevier, 2018-03)
In 2010 serotype O foot-and-mouth disease virus of the Mya98 lineage/SEA topotype spread into most East Asian countries. During 2010–2011 it was responsible for major outbreaks in the Republic of Korea where a monovalent ...
Genetic and subunit vaccines based on the stem domain of the equine influenza hemagglutinin provide homosubtypic protection against heterologous strains
(Elsevier, 2018-03-14)
H3N8 influenza virus strains have been associated with infectious disease in equine populations throughout the world. Although current vaccines for equine influenza stimulate a protective humoral immune response against ...
Molecular characterization of infectious bursal disease virus (IBDV) isolated in Argentina indicates a regional lineage
(2015-08)
In Argentina, classical vaccines are used to control infectious bursal disease virus (IBDV); however, outbreaks of IBDV are frequently observed. This could be due to failures in the vaccination programs or to the emergence ...
Identification of novel vaccine candidates for Chagas’ disease by immunization with sequential fractions of a trypomastigote cDNA expression library
(Elsevier, 2009-02)
The protozoan Trypanosoma cruzi is the etiological agent of Chagas´ disease, a major chronic infection in Latin America. Currently, there are neither effective drugs nor vaccines for the treatment or prevention of the ...
Optimized adenoviral vector that enhances the assembly of FMDV O1 virus-like particles in situ increases its potential as vaccine for serotype O viruses
(Frontiers Media, 2020-09)
Although replication-defective human adenovirus type 5 (Ad5) vectors that express in situ the capsid-encoding regions of Foot-and-mouth disease virus (FMDV) have proved to be effective as vaccines in relevant species for ...
An efficient vaccine against bovine leukemia virus
(BioMed Central, 2015)
Previous attempts to produce a vaccine against BLV faced problems of efficacy (i.e. only a fraction of animals were protected), persistence (i.e. rapid decrease of immune protection), cost (e.g. production of purified ...
New Approaches for the design of DNA vaccine vectors delivered by lactic acid bacteria
(MedCrave Group, 2017-12-05)
Lactic Acid Bacteria (LAB) have been bioengineered for mucosal delivery of prophylactic, pro-inflammatory and useful molecules that include bioactive peptides, cytokines, enzymes, allergens and DNA. One of the many benefits ...
Heterogeneity in the antibody response to foot‐and‐mouth disease primo‐vaccinated calves
(2015-06)
Foot‐and‐mouth disease (FMD) vaccines are routinely used as effective control tools in large regions worldwide and to limit outbreaks during epidemics. Vaccine‐induced protection in cattle has been largely correlated with ...