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Toxicological studies on alcoholic extracts of Loranthaceae from northwestern Argentine
(Instituto de Investigación de las Ciencias Exactas Físicas y Naturales, 2006-12)
The use of medicinal plants for the treatment of a variety of health affections has been increased during the last decades. Scientific publications attribute multiple biological activities to plant extracts. However, not ...
Preclinical studies on the pharmacokinetics, safety, and toxicology of oxfendazole: toward first in human studies
(SAGE Publications, 2015)
A 2-week study in rats identified target organs of oxfendazole toxicity to be bone marrow, epididymis, liver, spleen, testis, and thymus. Female rats had greater oxfendazole exposure and exhibited toxicities at lower doses ...
Genetic structure of deltamethrin-resistant populations of Triatoma infestans (Hemiptera: Reduviidae) in the Gran Chaco
(Springer, 2020-10)
The genetic structure of natural populations offers insight into the complexities of their dynamics, information that can be relevant to vector control strategies. Microsatellites are useful neutral markers to investigate ...
A machine learning model to predict drug transfer across the human placenta barrier
(Frontiers Media, 2021-07)
The development of computational models for assessing the transfer of chemicals across the placental membrane would be of the utmost importance in drug discovery campaigns, in order to develop safe therapeutic options. We ...
Prediction of non-genotoxic carcinogenicity based on genetic profiles of short term exposure assays
(Korean Society of Toxicology, 2016-06)
Non-genotoxic carcinogens are substances that induce tumorigenesis by non-mutagenic mechanisms and long term rodent bioassays are required to identify them. Recent studies have shown that transcription profiling can be ...
Novel use of Penicillium nalgiovense on stuffed semi–hard and hard cheeses
(Elsevier Science, 2019-08)
Penicillium nalgiovense is not used intentionally by the dairy industry although it is a well-known species for meat products. The aim of this study was to select P. nalgiovense strains characterized in their genetic ...
Genetic and biochemical biomarkers in the macrophyte Bidens laevis L. Exposed to a commercial formulation of endosulfan
(Wiley, 2014-09)
Previous studies in the wetland macrophyte Bidens laevis L have demonstrated that the insecticide endosulfan induces a high frequency of somatic chromosome aberrations in anaphase–telophase (CAAT) but no DNA changes as ...
Evaluation of genetic damage in pesticides applicators from the province of Córdoba, Argentina
(Springer Heidelberg, 2019-07)
The impact evaluation of pesticide exposure is conducted using combined data from biomonitoring and environmental monitoring. Damage to the human genome is, probably, the leading cause of chronic-degenerative disorders, ...