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Cav1.1 controls frequency-dependent events regulating adult skeletal muscle plasticity
(The Company of Biologists, 2013)
An important pending question in neuromuscular biology is how skeletal muscle cells decipher the stimulation pattern coming from
motoneurons to define their phenotype as slow or fast twitch muscle fibers. We have previously ...
Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells
(2010)
Inositol 1,4,5-trisphosphate (IP3) receptors (IP3Rs) drive calcium signals involved in skeletal muscle excitation-transcription coupling and plasticity; IP3R subtype distribution and downstream events evoked by their ...
Electrical stimulation induces calcium-dependent up-regulation of neuregulin-1β in dystrophic skeletal muscle cell lines
(2012)
Duchenne muscular dystrophy (DMD) is a
neuromuscular disease originated by reduced or no
expression of dystrophin, a cytoskeletal protein that
provides structural integrity to muscle fibres. A
promising pharmacological ...
Dihydropyridine receptors as voltage sensors for a depolarization-evoked, IP3R-mediated, slow calcium signal in skeletal muscle cells
(Rockefeller University Press, 2003)
The dihydropyridine receptor (DHPR), normally a voltage-dependent calcium channel, functions in skeletal muscle essentially as a voltage sensor, triggering intracellular calcium release for excitation-contraction coupling. ...
Ca(v)1.2 Activity and Downstream Signaling Pathways in the Hippocampus of An Animal Model of Depression
(MDPI, 2020)
Functional and morphological modifications in the brain caused by major mood disorders involve many brain areas, including the hippocampus, leading to cognitive and mood alterations. Ca(v)1.2 channel expression has been ...