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Characterization of the rat exploratory behavior in the elevated plus-maze with Markov chains
(ELSEVIER SCIENCE BV, 2010)
The elevated plus-maze is an animal model of anxiety used to study the effect of different drugs on the behavior of the animal It consists of a plus-shaped maze with two open and two closed arms elevated 50 cm from the ...
Characterization of rat behavior in the elevated plus-maze using a directed graph
(ELSEVIER SCIENCE BV, 2009)
The elevated plus-maze is a device widely used to assess rodent anxiety under the effect of several treatments, including pharmacological agents. The animal is placed at the center of the apparatus, which consists of two ...
Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus
(SAGE PUBLICATIONS LTD, 2010)
The present work aimed to evaluate the effects of social separation for 14 days (chronic stress) and of withdrawal from a 14-day treatment with diazepam (acute stress) on the exploratory behaviour of male rats in the ...
Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus
(Sage Publications Ltd, 2010-05-01)
The present work aimed to evaluate the effects of social separation for 14 days (chronic stress) and of withdrawal from a 14-day treatment with diazepam (acute stress) on the exploratory behaviour of male rats in the ...
Longitudinal study of daily variation of rats' behavior in the elevated plus-maze
(Elsevier B.V., 2003-01-01)
We conducted a longitudinal study about daily variation of Wistar male rats' behavior in the elevated plus-maze (EPM) evaluated in the 1st, 2nd, 3rd, 6th, 12th, and 18th months of life. Animals were submitted to the plus-maze ...
Central, but not basolateral, amygdala involvement in the anxiolytic-like effects of midazolam in rats in the elevated plus maze
(SAGE PUBLICATIONS LTDLONDON, 2012)
The role of the amygdala in the mediation of fear and anxiety has been extensively investigated. However, how the amygdala functions during the organization of the anxiety-like behaviors generated in the elevated plus maze ...
Effect of early malnutrition and environmental stimulation in the performance of rats in the elevated plus maze
(ELSEVIER SCIENCE BV, 2009)
Malnourished rats since birth (mothers fed on 6% of protein) or controlled ones (16% of protein), half of each group received environmental stimulation (ES) from the age of 0-35th day, were studied. The performance in the ...
ETHOPHARMACOLOGICAL ANALYSIS OF RAT BEHAVIOR ON THE ELEVATED PLUS-MAZE
(Elsevier B.V., 1994-09-01)
Behavioral categories were measured in rats left on an elevated plus-maze for 5 min, in addition to the traditional measures. Four independent factors emerged from a factor analysis. The variables that loaded highly and ...
Behavioural alterations provoked by prolonged calcitonin administration in rats
(2003-07-01)
Present work investigated the effect of prolonged administration of salmon calcitonin, a hormone secreted by parafollicular cells from thyroid, on behavioural parameters of rats. Animals received calcitonin sc, 100 mUI/100 ...
Dose-response effects of systemic anandamide administration in mice sequentially submitted to the open field and elevated plus-maze tests
(Associação Brasileira de Divulgação Científica, 2009)
The endocannabinoid system is involved in the control of many physiological functions, including the control of emotional states. In rodents, previous exposure to an open field increases the anxiety-like behavior in the ...