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Characterization of the molecular changes associated with the overexpression of a novel epithelial cadherin splice variant mRNA in a breast cancer model using proteomics and bioinformatics approaches: identification of changes in cell metabolism and an in
(Springer, 2019-05)
Breast cancer (BC) is the most common female cancer and the leading cause of cancer death in women worldwide. Alterations in epithelial cadherin (E-cadherin) expression and functions are associated to BC, but the underlying ...
Identification of a novel human E-Cadherin splice variant andassessment of its effects upon EMT-related events
(Wiley, 2016-12)
Epithelial Cadherin (E-cadherin) is involved in calcium-dependent cell-cell adhesion and signal transduction. The E-cadherin decrease/loss is a hallmark of Epithelial to Mesenchymal Transition (EMT), a key event in tumor ...
Análisis de alteraciones moleculares de SPOP, FOXA1 e IDH1 en cáncer de próstata de población colombiana y sus posibles implicaciones en el pronóstico
(Universidad Nacional de ColombiaBogotá - Ciencias - Maestría en Ciencias - BioquímicaDepartamento de QuímicaFacultad de CienciasBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá, 2021-04-23)
El cáncer de próstata (CaP) es el tipo de cáncer con mayor incidencia y mortalidad en nuestro país. Los actuales marcadores del pronóstico de la enfermedad no diferencian los casos agresivos de los indolentes con suficiente ...