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Development and validation of a dissolution test for diltiazem hydrochloride in immediate release capsules
(Sociedade Brasileira de Química, 2011-01-01)
This work describes the development and validation of a dissolution test for 60 mg of diltiazem hydrochloride in immediate release capsules. The best dissolution in vitro profile was achieved using potassium phosphate ...
Força de compressão e umidade no perfil de dissolução da hidroclorotiazida
(2006-01-01)
The aim of this work was to evaluate the influence of compression force and humidity in the dissolution profile of tablets formulation. As hidroclorotyiazide presents real problems of bioavailability, it was incorporate ...
A discriminating dissolution method for glimepiride polymorphs
(Wiley-Blackwell, 2012-02-01)
Glimepiride, an oral antidiabetic drug, is practically insoluble in water and exists in two polymorphic forms, I and II, of which form II has higher solubility in water. Because the dissolution rate of drugs can depend on ...
Ag precipitation and dissolution reactions in the Cu-3 wt.% Al-4 wt.% Ag alloy
(Elsevier B.V., 2006-12-15)
The Ag precipitation and dissolution reactions in the Cu-3 wt.% Al-4 wt.% Ag alloy were studied using isothermal and non-isothermal analyses. The activation energy values, obtained for the Ag precipitation reaction indicated ...
Simultaneous acquisition of the dissolution curves of two active ingredients in a binary pharmaceutical association, employing an on-line circulation system and chemometrics-assistance
(Elsevier, 2013-01)
The association of an on-line circulation system with a chemometrics-assisted UV detection strategy is described as a useful system to continuously monitor the dissolution of a pharmaceutical preparation containing two ...
Albendazole Solid Dispersions: Influence of Dissolution Medium Composition on In Vitro Drug Release
(Dissolution Technologies, Inc, 2014-01)
The rate-limiting step to drug absorption is often dissolution from the dosage form, especially for poorly soluble com-pounds. Two possibilities for improving the dissolution of these drugs are to increase the available ...
Solid dispersions containing Albendazole: Influence of dissolution media composition on in vitro drug release
(Dissolution Technologies, Inc, 2014-05)
The rate-limiting step to drug absorption is often dissolution from the dosage form, especially for poorly soluble com-pounds. Two possibilities for improving the dissolution of these drugs are to increase the available ...
Using Fluid Bed Granulation to Improve the Dissolution of Poorly Water-Soluble Drugs
(INST TECNOLOGIA PARANACURITIBA-PARANA, 2012)
In this study, fluid bed granulation was applied to improve the dissolution of nimodipine and spironolactone, two very poorly water-soluble drugs. Granules were obtained with different amounts of sodium dodecyl sulfate and ...
Using fluid bed granulation to improve the dissolution of poorly water-soluble drugs
(Brazilian Archives of Biology and Technology, 2012)
In this study, fluid bed granulation was applied to improve the dissolution of nimodipine and spironolactone, two very poorly water-soluble drugs. Granules were obtained with different amounts of sodium dodecyl sulfate and ...
Obtention and Evaluation of Inclusion Complexes of Furosemide with beta-ciclodextrin and hidroxipropil-beta-ciclodextrin: Effects on Drug`s Dissolution Properties
(COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES, 2008)
Obtention and Evaluation of Inclusion Complexes of Furosemide with beta-ciclodextrin and hidroxipropil-beta-ciclodextrin: Effects on Drug`s Dissolution Properties. The purpose of this study was to prepare, characterize and ...