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THE TRUE NATURE OF ZOONOSES: THE IDENTITY OF TRANSMISSIBLE DISEASES IN MAN AND IN OTHER VERTEBRATES
(Universidade Federal de Goiás, 2017)
Animal models of chronic pain. Are naturally occurring diseases a potential model for translational research?Animal models of chronic pain. Are naturally occurring diseases a potential model for translational research?
(Faculty of Veterinary Sciences - Universidad Austral de Chile, 2021)
Quality of Reporting and Adherence to ARRIVE Guidelines in Animal Studies for Chagas Disease Preclinical Drug Research: A Systematic Review
(Public Library of Science, 2015-11)
Publication of accurate and detailed descriptions of methods in research articles involving animals is essential for health scientists to accurately interpret published data, evaluate results and replicate findings. ...
Cannabidiol-Enriched Extract Reduced the Cognitive Impairment but Not the Epileptic Seizures in a Lafora Disease Animal Model
(Mary Ann Liebert, 2020-06)
Introduction: Lafora disease (LD) is a rare form of progressive infantile epilepsy in which rapid neurological deterioration occurs as the disease advances, leading the patients to a vegetative state and then death, usually ...
Neuroprotective effects associated with immune modulation by selected lactic acid bacteria in a Parkinson's disease model
(Elsevier Science Inc, 2020-11)
Objectives: Parkinson's disease (PD) is a neurodegenerative process that affects the motor function and involves an inflammatory response and B vitamin deficiencies. The aim of this study was to evaluate the effect of ...
THE CRICKETS(ACHETA DOMESTICUS) AS AN ANIMAL MODEL TO STUDY PARKINSON'S DISEASELOS GRILLOS (ACHETA DOMESTICUS) COMO MODELO ANIMAL PARA ESTUDIAR LA ENFERMEDAD DE PARKINSON
(Facultad de Ciencias Químico Farmacéuticas y Bioquímicas, 2022)
Refining drug administration in a murine model of acute infection with Trypanosoma cruzi
(BioMed Central, 2020-10)
Background: In animal research, "refinement" refers to modifications of husbandry or experimental procedures to enhance animal well-being and minimize or eliminate pain and distress. Evaluation of drug efficacy in mice ...
Neuroprotective effects of human umbilical cord mesenchymal stromal cells in an immunocompetent animal model of Parkinson's disease
(Elsevier Science, 2012-05)
Microglial activation in the substantia nigra (SN) is a ubiquitous feature in PD which could mediate toxic effects. Human mesenchymal stromal cells (hMSCs) possess immunomodulatory properties. We evaluated whether the ...
Mechanisms of Antiparkinsonian Anticholinergic Therapy Revisited
(Pergamon-Elsevier Science Ltd, 2021-07)
Before the advent of L-DOPA, the gold standard symptomatic therapy for Parkinson's disease (PD), anticholinergic drugs (muscarinic receptor antagonists) were the preferred antiparkinsonian therapy, but their unwanted side ...
Animal models of fetal programming: Focus on chronic maternal stress during pregnancy and neurodevelopment
(Elsevier, 2017)
Animal models of fetal programming contribute in three synergistic ways to understanding and treating human diseases or predispositions to diseases, which emerge from in utero insults leading to fetal programming. Firstly, ...