Now showing items 1-4 of 4
The first step of the dioxygenation reaction carried out by tryptophan dioxygenase and indoleamine 2,3-dioxygenase as revealed by quantum mechanical/molecular mechanical studies
Tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) are two heme-containing enzymes which catalyze the conversion of L-tryptophan to N-formylkynurenine (NFK). In mammals, TDO is mostly expressed in liver and ...
Critical role of the solvent environment in galectin-1 binding to the disaccharide lactose
(American Chemical Society, 2009-12)
Galectin-1 (Gal-1), a member of a family of evolutionarily conserved glycan-binding proteins, binds specifically to poly-N-acetyllactosamine-enriched glycoconjugates. Through interactions with these glycoconjugates, this ...
Amphiphilic tricationic Zn(II)phthalocyanine provides effective photodynamic action to eradicate broad-spectrum microorganisms
(Royal Society of Chemistry, 2021-07)
A novel tricationic Zn(II)phthalocyanine derivative, (NCH3)3ZnPc3+, was synthesized by ring expansion reaction of boron(III) [2,9(10),16(17)-trinitrosubphthalocyaninato]chloride. First, the reaction of this subphthalocyanine ...
Photosensitized Formation of Soluble Bionanoparticles of Lysozyme
(John Wiley & Sons Ltd, 2021-12)
Photosensitized crosslinking of hen egg-white lysozyme (LZ) in buffer solutions was obtained by blue-LED excitation of ruthenium (II) tris-bipyridyl dication (Ru(bpy)32+) in a molar excess of persulfate anion (S2O82−), ...