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In situ Formed Implants, Based on PLGA and Eudragit Blends, for Novel Florfenicol Controlled Release Formulations
(John Wiley & Sons Inc, 2020-11)
Drug controlled release technologies (DCRTs) represent an opportunity for designing new therapies. Main objectives are dose number optimization and secondary effects reduction to improve the level of patient/client acceptance. ...
Flavor release by enzymatic hydrolysis of starch samples containing vanillin-amylose inclusion complexes
(Elsevier Science, 2014-05)
Hylon VII is a high amylose corn starch which has excellent gelling properties, and its behavior as flavor encapsulant is relevant to the food industry because its ability to regulate a swelling-controlled release in aqueous ...
Encapsulation of florfenicol by in situ crystallization into novel alginate-Eudragit RS® blended matrix for pH modulated release
(Editions Sante, 2019-12)
Florfenicol (FF) is a broad-spectrum antibiotic with the drawback of poor solubility in physiological media. Despite vehiculization of FF become an alternative, current devices usually showed low encapsulation efficiencies(EE) ...
Nanomedicine applied to cardiovascular diseases: Latest developments
(SAGE Publications, 2017-04)
Cardiovascular diseases are a major cause of disability and they are currently responsible for a significant number of deaths in a large percentage of the world population. A large number of therapeutic options have been ...
Oil-in-water emulsion development for the encapsulation and sustained release of xanthone
(Taylor & Francis, 2020-02)
In the present work, an oil-in-water emulsion was developed for the encapsulation of xanthone, a potent anti-inflammatory and antitumor molecule of natural source. The xanthone is insoluble in water so it was encapsulated ...
Development of a dissolution method based on lipase for preclinical level A IVIVC of oral poly(ε-caprolactone) microspheres
(Editions Sante, 2019-08)
Level A in vitro/in vivo correlation (IVIVC) of poly (ε-caprolactone) (PCL) microspheres for oral administration is challenging since in vitro PCL dissolution takes longer. The aims of this study were: 1) to develop three ...
Uptake and release of Dexamethasone using pH-responsive poly (2-hydroxyethyl methacrylate-co-2-(diisopropylamino) ethyl methacrylate) hydrogels for potential use in ocular drug delivery
(Editions Sante, 2019-02)
pH-responsive hydrogels prepared by copolymerization between 2-hydroxyethyl methacrylate (HEMA) and 2-(diisopropylamino)ethyl methacrylate (DPA) appear to be a promising system for controlling Dexamethasone 21-disodium ...
Controlled fluoride release for osteoporosis treatment using orally administered chitosan hydrogels
(Editions Sante, 2019-06)
Chitosan - β-glycerophosphate hydrogels have been widely studied for biomedical applications in recent years. In the current study a Chitosan - β-glycerophosphate hydrogel was evaluated as a platform for sodium fluoride ...
Effect of processing techniques on new poly(ε-caprolactone)-embelin microparticles of biomedical interest
(John Wiley & Sons Inc, 2017-03)
Poly(ε-caprolactone) microparticles containing embelin (PCLE) are prepared by electrohydrodynamic atomization (EHDA) and emulsion-solvent evaporation techniques. Microparticles are characterized in terms of drug state, ...