We have devised a new caged GABA based on ruthenium bipyridyl coordination chemistry. This photo-trigger delivers GABA upon irradiation with wavelengths up to 532 nm undergoing heterolytic photo-cleavage, in a clean and ...

A short and efficient methodology for the synthesis of chiral dioxa-caged Compounds from levoglucose-none, a biomass-derived enone, is herein Presented. The key transformation, that involves a cascade 3-step cationic ...

We present a photocleavable protecting group based on ruthenium bipyridyl complexes and suitable for amino acid photodelivery. We discuss the photochemical properties of the caged glutamate, which is a major neurotransmitter ...

We introduce a novel caged dopamine compound (RuBi-Dopa) based on ruthenium photochemistry. RuBi-Dopa has a high uncaging efficiency and can be released with visible (blue-green) and IR light in a two-photon regime. We ...

We report the synthesis, characterization and applications of a ruthenium-bipyridine based caged nicotine. The complex [Ru(bpy)2(nic)2]2+ (where bpy=2,2' bipyridine and nic=nicotine (3-[(2S)-1-methylpyrrolidin-2-yl] ...

Caged near-IR emitting fluorescent dyes are in high demand in optical microscopy but up to now were unavailable. We discovered that the combination of a carbopyronine dye core and a photosensitive 2-diazo-1-indanone residue ...

Octahedral Ru(II) polypyridyl complexes constitute a superb platform to devise photoactive triggers capable of delivering entire molecules in a reliable, fast, efficient and clean way. Ruthenium coordination chemistry opens ...

Inhibiting with visible light. An inorganic‐based caged compound of the inhibitory neurotransmitter, γ‐amino butyric acid (GABA), was prepared and photolysed by light at 450 nm with the highest uncaging quantum yield ...

A visible-light activatable caged compound based on a ruthenium-polypyridine complex was used to elicit the feeding response of the freshwater cnidarian Hydra vulgaris. The phototrigger delivers l-arginine in a clean ...