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Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness
(Wiley, 2014-07)
Muscle wasting and cachexia are important systemic manifestations of highly prevalent conditions including cancer. Inflammation, oxidative stress, autophagy, ubiquitin-proteasome system, nuclear factor (NF)-kB, and mitogen ...
Gut Hormones, Appetite Suppression and Cachexia in Patients with Pulmonary TB
(Public Library of Science, 2013)
Background: Cachexia is a hallmark of pulmonary tuberculosis and is associated with poor prognosis. A better understanding of the mechanisms behind such weight loss could reveal targets for therapeutic intervention. The ...
Pharmacological activity of quercetin and 5-caffeoylquinic acid oral intake in male Balb/c mice with lung adenocarcinoma
(Elsevier Science Inc., 2020-01)
Lung adenocarcinoma (LAC) is a major worldwide cause of death by cancer, it shows high aggressiveness, functional decline, systemic compromise and severecachexia, which might be counteracted by dietary redox-active ...
Optimizing aminoglycoside selection for KPC-producing Klebsiella pneumoniae with the aminoglycoside-modifying enzyme (AME) gene aac(6')-Ib
(Oxford University Press, 2021)
OBJECTIVES: KPC-producing Klebsiella pneumoniae (KPC-Kp) isolates commonly co-harbour the aminoglycoside-modifying enzyme (AME) gene aac(6')-Ib, which encodes an AME that can confer resistance to some of the commercially ...
Aminoglycoside-resistance gene signatures are predictive of aminoglycoside MICs for carbapenem-resistant Klebsiella pneumoniae.
(Oxford University Press, 2022)
BACKGROUND: Aminoglycoside-containing regimens may be an effective treatment option for infections caused by carbapenem-resistant Klebsiella pneumoniae (CR-Kp), but aminoglycoside-resistance genes are common in these ...
Canine Cystitis Caused by Salmonella enterica subsp. enterica
(Universidade Federal do Rio Grande do Sul, 2019)
Asthenia hypophysopriva: neuromuscular symptoms due to alterations in the pituitary
(Massachusetts Medical Society, 1936)
In the advanced stages of confirmed pituitary insufficiency there is a neuromuscular asthenic syndrome which occurs constantly, intensely and characteristically in the toad, during certain stages in the rat, and in a less ...
Type B Insulin Resistance in Peru
(Elsevier, 2016)
Type B insulin resistance (IR) is a rare autoimmune disease characterized by the presence of insulin receptor autoantibodies, resulting in a marked IR inducing hyperglycemia. Our first case is a 42-year-old female with a ...
Cryptosporidium varanii infection in leopard geckos (Eublepharis macularius) in Argentina
(Faculty of Veterinary Medicine, University of Tripoli and National Authority for Scientific Research, 2016-06-28)
Cryptosporidiosis is observed in reptiles with high morbidity and considerable mortality. The objective of this study was to achieve the molecular identification of Cryptosporidium spp. in pet leopard geckos (Eublepharis ...
Schistosomiasis and Strongyloidiasis Recommendations for Solid-Organ Transplant Recipients and Donors
(Wolters Kluwer Health, 2018)
Schistosomiasis is a geographically restricted disease caused by several species of the trematode worm Schistosoma. If untreated, it can lead to major disability and death. Typically, only nonspecific symptoms, such as ...