Buscar
Mostrando ítems 1-10 de 10
Hypoxia in high glucose followed by reoxygenation in normal glucose reduces the viability of cortical astrocytes through increased permeability of connexin 43 hemichannels
(WILEY-LISS, 2010)
Brain ischemia causes more extensive injury in hyperglycemic than normoglycemic subjects, and the increased damage is to astroglia as well as neurons. In the present work, we found that in cortical astrocytes from rat or ...
Role of astrocyte connexin hemichannels in cortical spreading depression
(2018)
Cortical spreading depression (CSD) is an intriguing phenomenon consisting of massive slow brain depolarizalions that affects neurons and glial cells. It has been recognized since 1944, but its pathogenesis has only been ...
Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culturePROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAPROC NATL ACAD SCI USA
(NATIONAL ACADEMY OF SCIENCES, 2017)
Atp and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
(WILEY-BLACKWELL, 2011)
Inflammation contributes to neurodegeneration in post-ischemic brain, diabetes, and Alzheimer's disease. Participants in this inflammatory response include activation of microglia and astrocytes. We studied the role of ...