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Structure of a Lys49-Phospholipase A2 homologue isolated from the venom of Bothrops nummifer (jumping viper)
(1999-02)
Lys49-Phospholipase A2 (Lys49-PLA2) homologues damage membranes by a Ca2+-independent mechanism which does not involve catalytic activity. We have solved the structure of myotoxin-I, a Lys49-PLA2 homologue isolated from ...
Myotoxin II from Bothrops asper (Terciopelo) venom is a lysine-49 phospholipase A2
(1991)
A basic, dimeric myotoxic protein, myotoxin II, purified from Bothrops asper venom has a similar molecular weight and is immunologically cross-reactive with antibodies raised to previously isolated B. asper phospholipases ...
High-Resolution Crystal Structure of the Snake Venom Metalloproteinase BaP1 Complexed with a Peptidomimetic: Insight into Inhibitor Binding
(2009-07-07)
BaP1, a zinc-dependent endopeptidase belonging to the P-I class of snake venom metalloproteinases, exerts multiple tissue-damaging activities, leading to hemorrhage, myonecrosis, dermonecrosis, blistering, and edema. ...
Backbone Flexibility Controls the Activity and Specificity of a Protein−Protein Interface: Specificity in Snake Venom Metalloproteases
(2010-07-09)
Protein-protein interfaces have crucial functions in many biological processes. The large interaction areas of such interfaces show complex interaction motifs. Even more challenging is the understanding of (multi)specificity ...
Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: the N-terminal region is more important than enzymatic activity
(2006-05)
Several snake venom secreted phospholipases A2 (sPLA2s) including OS2 exert a variety of pharmacological effects ranging from central neurotoxicity to anti-HIV activity by mechanisms that are not yet fully understood. To ...
Inhibition of Myotoxic Activity of Bothrops asper Myotoxin II by the Anti-trypanosomal Drug Suramin
(2005-06-15)
Suramin, a synthetic polysulfonated compound, developed initially for the treatment of African trypanosomiasis and onchocerciasis, is currently used for the treatment of several medically relevant disorders. Suramin, ...
Organic Acids without a Carboxylic Acid Functional Group
(Journal of Chemical Education 77(7):910-915. July 2000, 2000-07)
This paper presents several organic molecules that have been labeled as acids but do not contain a carboxylic acid functional group. The rationale for the nomenclature and appropriate explanations for the apparent acidity ...
Efecto del grado de sustitución de harina de trigo con harina de pejibaye (Bactris Gasipaes H.B.K.) sobre las características sensoriales de un queque seco
(Reviteca, Volumen 10, 2004, 2004)
Se evaluó el efecto de la sustitución de harina de trigo con harina de pejibaye en cuatro niveles (10%, 15%, 20% y 25%) sobre la intensidad de varias propiedades sensoriales de un queque seco. Los queques se prepararon a ...
Some Thoughts on Christianity and Sports
(Conquista Cristiana Enero/Febrero, 1991, 1991-01)
There is a need to discuss, starting from some basic Christian truths, to what extent the Christian and athletic ideals are compatible; how sports could help modern men and women to be better Christians, and what kind of ...
Structure of a calcium-independent phospholipase-like myotoxic protein from Bothrops asper venom
(1995-05-01)
Myotoxin II, a myotoxic calcium-independent phospholipase-like protein isolated from the venom of Bothrops asper, possesses no detectable phospholipase activity. The crystal structure has been determined and refined at 2.8 ...