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Polygenic risk prediction and SNCA haplotype analysis in a Latino Parkinson's disease cohort
(Elsevier, 2022)
Background: Large-scale Parkinson's disease (PD) genome-wide association studies (GWAS) have, until recently, only been conducted on subjects with European-ancestry. Consequently, polygenic risk scores (PRS) constructed ...
Intragenerational social mobility and self-rated oral health in the british cohort study
(Springer, 2021)
Background: Most studies on social mobility and oral health have focused on movement between generations (intergenerational mobility) rather than movement within an individual’s own lifetime (intragenerational mobility). ...
Cancer Mortality in Córdoba, Argentina, 1986–2006: An Age-Period-Cohort Analysis
(Pensiero Scientifico Editor, 2018-01)
Aims and background. Cancer is the second main cause of death in Argentina, surpassed only by cardiovascular disease. However, analytical approaches isolating some of the known effects, such as age at death, period of death ...
Longitudinal association between food frequency and changes in body mass index: a prospective cohort study
(BMJ Publishing Group, 2020)
OBJECTIVES: Analysing data of the Young Lives Study in Peru, we aimed at assessing the association between daily food frequency and body mass index (BMI) changes between 2006 and 2016. DESIGN: Secondary analysis of a ...
A comparison of seven cox regression-based models to account for heterogeneity across multiple HIV treatment cohorts in Latin America and the Caribbean
(Mary Ann Liebert, 2015)
Many studies of HIV/AIDS aggregate data from multiple cohorts to improve power and generalizability. There are several analysis approaches to account for cross-cohort heterogeneity; we assessed how different approaches can ...
Is grandparents' social class associated with adult grandchildren's oral health? Analysis of two British cohorts
(Wiley, 2020)
OBJECTIVES: No studies have taken a multigenerational approach to the study of oral health inequalities. This study investigated whether grandparents' social class was associated with adult grandchildren's oral health. ...
The risk of mortality among people with type 2 diabetes in Latin America: A systematic review and meta-analysis of population-based cohort studies
(Wiley, 2019)
Type 2 diabetes mellitus (T2DM) is associated with a high mortality risk, although the magnitude of this association remains unknown in Latin America (LA). We aimed to assess the strength of the association between T2DM ...
Rapid diagnosis of tuberculosis with the Xpert MTB/RIF assay in high burden countries: A cost-effectiveness analysis
(Public Library of Science, 2011)
Background: Xpert MTB/RIF (Xpert) is a promising new rapid diagnostic technology for tuberculosis (TB) that has characteristics that suggest large-scale roll-out. However, because the test is expensive, there are concerns ...