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Circulating levels of brain-derived neurotrophic factor: correlation with mood, cognition and motor function
(FUTURE MEDICINE LTD, 2010)
Brain-derived neurotrophic factor (BDNF) is the most widely distributed neurotrophin in the CNS, where it plays several pivotal roles in synaptic plasticity and neuronal survival. As a consequence, BDNF has become a key ...
Platelet GSK3B activity in patients with late-life depression: Marker of depressive episode severity and cognitive impairment?
(INFORMA HEALTHCARE, 2011)
Objective. Increased GSK3B activity has been reported as a state marker of major affective episodes in patients with depression and bipolar disorder. No study so far has addressed GSK3B activity in late-life depression. ...
The renin-angiotensin system is upregulated in the cortex and hippocampus of patients with temporal lobe epilepsy related to mesial temporal sclerosis
(BLACKWELL PUBLISHING, 2008)
Purpose: As reported by several authors, angiotensin II (AngII) is a proinflammatory molecule that stimulates the release of inflammatory cytokines and activates nuclear factor kappa B (NF kappa B), being also associated ...