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Breve historia de la bioinformática.
(2013-07-12)
La bioinformática es el resultado de la unión indisoluble entre las tecnologías informáticas y las ciencias biológicas. Fue
concebida en principio para resolver interrogantes como los siguientes: ¿cómo almacenar y organizar ...
Editorial: User-friendly tools applied to genetics or systems biology
(Frontiers Media, 2020)
Role of non-coding regulatory RNA in the virulence of human pathogenic vibrios
(Frontiers Media, 2017)
In recent decades, the identification of small non-coding RNAs in bacteria has revealed
an important regulatory mechanism of gene expression involved in the response to
environmental signals and to the control of virulence. ...
Bioinformatic prediction and experimental verification of Fur-regulated genes in the extreme acidophile Acidithiobacillus ferrooxidans
(2007)
The gamma-proteobacterium Acidithiobacillus ferrooxidans lives in extremely acidic conditions (pH 2) and, unlike most organisms, is confronted with an abundant supply of soluble iron. It is also unusual in that it oxidizes ...
Sequencing, bioinformatic characterization and expression pattern of a putative amino acid transporter from the parasitic cestode Echinococcus granulosus
(ELSEVIER, 2008-03-31)
We have sequenced and partially characterized an Echinococcus granulosus cDNA, termed egat1, from a protoscolex signal sequence trap (SST) cDNA library. The isolated 1627 bp long cDNA contains an ORF of 489 amino acids and ...
Bioinformatic Prediction of Gene Functions Regulated by Quorum Sensing in the Bioleaching Bacterium Acidithiobacillus ferrooxidans
(2013)
The biomining bacterium Acidithiobacillus ferrooxidans oxidizes sulfide ores
and promotes metal solubilization. The efficiency of this process depends on the
attachment of cells to surfaces, a process regulated by quorum ...
New players in neuronal Iron homeostasis: insights from CRISPRi studies
(MDPI, 2022)
Selective regional iron accumulation is a hallmark of several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. The underlying mechanisms of neuronal iron dyshomeostasis have been studied, ...
Bioinformática multifractal : Una propuesta hacia la interpretación no-lineal del genoma.
(2015-05-11)
El primer borrador de la secuencia completa del genoma humano (GH) se publicó en el año 2001 por parte de dos
consorcios competidores. Desde entonces, varias características estructurales y funcionales de la organización ...
Binding of dihydroxynaphthyl aryl ketones to tubulin colchicine site inhibits microtubule assembly
(Elsevier, 2015)
Dihydroxynaphthyl aryl ketones 1e5 have been evaluated for their abilities to inhibit microtubule assembly
and the binding to tubulin. Compounds 3, 4 and 5 displayed competitive inhibition against
colchicine binding, and ...
Microarray and bioinformatic analyses suggest models for carbon metabolism in the autotroph Acidithiobacillus ferrooxidans
(ELSEVIER, 2006-09)
Acidithiobacillus ferrooxidans is a chemolithoautotrophic bacterium that uses iron or sulfur as an energy and electron source. Bioinformatic analysis of the A. ferrooxidans draft genome sequence was used to identify putative ...