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New insights into bacterial bile resistance mechanisms: the role of bile salt hydrolase and its impact on human health
(Elsevier Science, 2018-10)
Bile acids (BA), the major components of bile, are biological detergents that facilitate the emulsification and solubilization of dietary lipids and also display potent antimicrobial activity, the bacterial membranes being ...
Effect of Cynara scolymus and Silybum marianum extracts on bile production in pigs
(Garuda Scientific Publications, 2018-01)
Many of the beneficial effects on productive performance observed when vegetable extracts are incorporated as feed additives in intensive farming can be explained by an increase in bile production. An experiment was conducted ...
Effect of bile on the β-galactosidase activity of dairy propionibacteriaEffet de la bile sur l'activité β-galactosidase de bactéries propioniques laitières
(EDP Sciences, 2000-04)
In the present study, the effect of bile on the growth, cell permeabilization and β-galactosidase activity of dairy propionibacteria was determined. Two groups of strains with different behavior in media with oxgall ...
Aquaporin gene therapy for cholestasis
(John Wiley & Sons Inc, 2017-01)
This is regarding the editorial “Aquaporin gene therapy for disorders of cholestasis?” by Tradtrantip and Verkman.(1) We thank the authors for their comments in our recent studies.(2,3) Nevertheless, we believe that an ...
Adenoviral transfer of human aquaporin-1 gene to rat liver improves bile flow in estrogen-induced cholestasis
(Nature Publishing Group, 2014-08)
Estrogens can cause liver cholestatic disease. As downregulation of hepatocyte canalicular aquaporin-8 (AQP8) water channels has been involved in estrogen-induced bile secretory failure, we tested whether the archetypal ...
Vagally-mediates cholestatic and choleretic effects of centrally applied Endothelin-1 through ETA receptors
(Elsevier Science, 2006-12)
The role of Endothelin-1 (ET-1) in the central nervous system is not fully understood yet although several studies strongly support its neuromodulatory role. A high density of endothelin receptors is present in the dorsal ...
Impact of bile salt adaptation of Lactobacillus delbrueckii subsp. lactis 200 on its interaction capacity with the gut
(Elsevier Science, 2011-10)
In a previous work, bile-salt-resistant derivatives were obtained from non-intestinal lactobacilli. The aim of this work was to investigate the impact of bile adaptation of Lactobacillus delbrueckii subsp. lactis 200 on ...
Hepatic bile formation: Canalicular osmolarity and paracellular and transcellular water flow
(American Society for Pharmacology and Experimental Therapeutics, 2019-12)
The purpose of this minireview is to show that a new paradigm is developing regarding hepatic bile flow. The focus thus far has been on carrier-mediated transport of bile acids and other solutes, such as glutathione, which ...
Studies on the interactions between bile salts and food emulsifiers under in vitro duodenal digestion conditions to evaluate their bile salt binding potential
(Elsevier Science, 2019-02)
During the last decade a special interest has been focused on studying the relationship between the composition and structure of emulsions and the extent of lipolysis, driven by the necessity of modulate lipid digestion ...
Bile acids: Lipase-catalyzed synthesis of new hyodeoxycholic acid derivatives
(Elsevier Science Inc, 2018-12)
In this work we present an efficient, environmentally friendly approach to the synthesis of a series of hyodeoxycholic acid derivatives applying Biocatalysis. Fifteen acetyl and ester derivatives, twelve of them new, were ...