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Ketamine prevents seizures and reverses changes in muscarinic receptor induced by bicuculline in rats
(Elsevier, 2013-02)
The cholinergic system has been implicated in several experimental epilepsy models. In a previous study bicuculline (BIC), known to antagonize GABA-A postsynaptic receptor subtype, was administered to rats at subconvulsant ...
Picrotoxin but not bicuculline partially abolishes the cardio-inhibitory responses induced by visual stimulation in the crab Neohelice granulata
(Elsevier Inc, 2012-12)
Conspicuous and sustained heart arrests, revealed as an increase in the magnitude of cardiac interbeat intervals, are elicited in the crab Neohelice granulata upon the presentation of a visual danger stimulus (VDS). Aiming ...
Substance P depresses bioelectrical responses evoked in the nucleus tractus solitarii: Interaction with γ-aminobutyric acid-ergic neurons
(1992)
The effects of intracerebroventricular (i.c.v.) administration of substance P (SP) and γ-aminobutyric acid (GABA) on responses evoked in the nucleus tractus solitarii (NTS) by electrical stimulation of the ipsilateral ...
Modulation of synaptic transmission in hippocampal CA1 neurons by a novel neurotoxin (beta-pompilidotoxin) derived from wasp venom
(Elsevier B.V., 2001-12-01)
We examined the effects of beta-pompilidotoxin (beta-PMTX), a neurotoxin derived from wasp venom. on synaptic transmission in the mammalian central nervous system (CNS). Using hippocampal slice preparations of rodents, we ...
Opioidergic and GABAergic mechanisms in the rostral ventromedial medulla modulate the nociceptive response of vocalization in guinea pigs
(PERGAMON-ELSEVIER SCIENCE LTD, 2010)
Vocalization generated by the application of a noxious stimulus is an integrative response related to the affective-motivational component of pain. The rostral ventromedial medulla (RVM) plays an important role in descending ...
Bicuculline, a GABAA-receptor antagonist, blocked HPA axis activation induced by ghrelin under an acute stress
(Elsevier Science, 2017-03)
Ghrelin is a peptide of 28 amino acids with a homology between species, which acts on the central nervous system to regulate different actions, including the control of growth hormone secretion and metabolic regulation. ...
Glutamate and GABA neurotransmission are increased in paraventricular nucleus of hypothalamus in rats induced to 6-OHDA parkinsonism: Involvement of nNOS
(2019-07-01)
Aim: Parkinson's disease (PD) is a progressive neurodegenerative disease that manifests itself clinically after reaching an advanced pathological stage. Besides motor signals, PD patients present cardiovascular and autonomic ...
Role of raphe in the body temperature regulation of precocious birds
(2019-01-01)
Introduction: It is demonstrated in mammals that, at least in rats, caudal brain regions, such as raphe nuclei, are involved in the modulation of thermoeffectors for heat loss and heat production, such as peripheral ...
Benzodiazepine modulation of homomeric GABAAρ1 receptors: Differential effects of diazepam and 40´-chlorodiazepam
(Elsevier, 2014-09-22)
GABAA receptors (GABAARs) are ligand-gated ion channels that mediate inhibitory neurotransmission in the central nervous system (CNS). They are members of the Cys-loop receptor family and display marked structural and ...
POSSIBLE INTERACTION BETWEEN THE INFERIOR COLLICULUS AND THE SUBSTANTIA-NIGRA IN AUDIOGENIC-SEIZURES IN WISTAR RATS
(Pergamon-elsevier Science LtdOxfordInglaterra, 1991)