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Biopharmaceuticals from microorganisms: from production to purification
(2016-12-01)
The use of biopharmaceuticals dates from the 19th century and within 5–10 years, up to 50% of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical industry experienced a significant ...
Biopharmaceutics drug disposition classification system
(Springer Nature Switzerland AG, 2021)
The Biopharmaceutics Drug Disposition Classification System (BDDCS) is a revision of the Biopharmaceutics (or Biopharmaceutical) Classification System (BCS) that may be useful to predict routes of elimination and to foresee ...
Liquid–liquid extraction of biopharmaceuticals from fermented broth: trends and future prospects
(2018-07-01)
Biopharmaceuticals are one of the most important groups of biotechnological products, representing one-quarter of all pharmaceutical sales and providing suitable and efficient medical care for many previously untreatable ...
Pharmacovigilance of Biopharmaceuticals in Rheumatic Diseases, Adverse Events, Evolution, and Perspective: An Overview
(Biomedicines, 2020-08-23)
Since we have gained an understanding of the immunological pathophysiology of rheumatic diseases such as rheumatoid arthritis and systemic lupus erythematosus, treatment based on biological drugs has become a fundamental ...
Kasumi-1 cell line: an alternative to the potency assay of Filgrastim biopharmaceutical
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2018)
Introduction: Biopharmaceutics and pharmacokinetics
(Springer Nature Switzerland AG, 2018)
Biopharmaceutics and pharmacokinetics are pharmaceutical disciplines useful to improve the outcome of drug therapies, assist drug product development, and establish pharmacokinetics-pharmacodynamics models and in vitro-in ...
L-asparaginase production review: bioprocess design and biochemical characteristics
(2021-06-01)
Abstract: In the past decades, the production of biopharmaceuticals has gained high interest due to its great sensitivity, specificity, and lower risk of negative effects to patients. Biopharmaceuticals are mostly therapeutic ...
Comparative oral drug classification systems: Acetazolamide, azithromycin, clopidogrel, and efavirenz case studies
(American Chemical Society, 2018-08)
Biopharmaceutics classification systems based on the properties of solubility and permeability or the extension of metabolism are very important tools in the early stages of the development and regulatory stages of new ...