Introduction: Biopharmaceutics and pharmacokinetics

Abstract

Biopharmaceutics and pharmacokinetics are pharmaceutical disciplines useful to improve the outcome of drug therapies, assist drug product development, and establish pharmacokinetics-pharmacodynamics models and in vitro-in vivo correlations. Here, we introduce some essential lexicon that will be used throughout this volume and discuss the relationship between drug exposure and pharmacological response, in the framework of the free drug theory/hypothesis.