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Antiviral activity against dengue virus of diverse classes of algal sulfated polysaccharides
(Elsevier Science, 2012-11)
Diverse classes of sulfated polysaccharides obtained from the red seaweeds (Rhodophyta) Grateloupia indica, Scinaia hatei and Gracilaria corticata, the brown seaweeds (Phaeophyta) Stoechospermum marginatum and Cystoseira ...
Plant and animal steroids a new hope to search for antiviral agents
(Bentham Science Publishers, 2010-01)
Scientific literature provides evidence about the use of steroids as an adjunct treatment to antiviral therapies. Immunomodulatory activity of some steroids would account for the recovery in patients with herpetic and other ...
Anti-adenovirus activity of epiandrosterone and dehydroepiandrosterone derivatives
(Karger, 2010-05)
Background: Dehydroepiandrosterone (DHEA) exhibits a wide range of biological functions including antiviral activity. In this work, we present in vitro anti-adenovirus (AdV) activity of seven DHEA and twelve epiandrosterone ...
Antiviral activity of A771726, the active metabolite of leflunomide, against Junín virus
(Wiley-liss, Div John Wiley & Sons Inc, 2018-05)
The aim of this study was to investigate the effect of A771726, the active metabolite of leflunomide, (CONICET-UBA), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad against the infection with ...
Virucidal, antiviral and immunomodulatory activities of β-escin and Aesculus hippocastanum extract
(Wiley, 2018-11)
Objectives: β-Escin, one of the constituents of Aesculus hippocastanum L. (Hippocastanaceae) seed extract (AH), inhibits NF-κB activation, which plays an important role in HSV-1 replication. The aim was to examine the ...
Antiviral activity of the natural alkaloid anisomycin against dengue and Zika viruses
(Elsevier Science, 2020-04)
Flaviviruses constitute a public health concern because of their global burden and the lack of specific antiviral treatment. Here we investigated the antiviral activity of the alkaloid anisomycin against dengue (DENV) and ...
Structure and antiviral activity of sulfated fucans from Stoechospermum marginatum
(Pergamon-Elsevier Science Ltd, 2006-11)
A sulfated fucan containing fraction (SmWE) was isolated from water extract of the brown seaweed Stoechospermum marginatum collected from the Arabian Sea. Anion exchange chromatography of the crude fraction results in the ...
Changes in antiviral susceptibility to entry inhibitors and endocytic uptake of dengue-2 virus serially passaged in Vero and C6/36 cells
(Elsevier, 2014-02)
The aim of the present study was to analyze the influence of virus origin, mammalian or mosquito cell-derived, on antiviral susceptibility of DENV-2 to entry inhibitors and the association of this effect with any alteration ...
Synthesis and antiviral activity of some imidazo[1,2-b][1,3,4]thiadiazole carbohydrate derivatives
(Elsevier, 2019-07)
Herein we describe the synthesis of imidazo[2,1-b][1,3,4]thiadiazoles from carbohydrates with D-ribo and D-xylo configuration. The antiviral activity of these compounds was tested against Junín virus (the etiological agent ...
Structural features and antiviral activity of sulphated fucans from the brown seaweed Cystoseira indica
(International Medical Press, 2007-06)
Natural compounds offer interesting pharmacological perspectives for antiviral drug development. In this study, we have analysed sulphated-fucan-containing fractions isolated from the brown seaweed Cystoseira indica. The ...