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ATXN10 Microsatellite Distribution in a Peruvian Amerindian Population
(Springer, 2019)
Spinocerebellar ataxia type 10 (SCA10) is a repeat expansion disease occurring mostly in Latin America, suggesting that the mutation spread with the peopling of the Americas, or that Amerindian populations, have a higher ...
Distribution of the CAG Triplet Repeat in ATXN1, ATXN3, and CACNA1A Loci in Peruvian Population
(Springer, 2020)
Spinocerebellar ataxia subtypes 1, 3, and 6 (SCA1, MJD/SCA3, and SCA6) are among the most prevalent autosomal dominant cerebellar ataxias worldwide, but their relative frequencies in Peru are low. Frequency of large normal ...
Single step strategy for estimating unknown STR allele frequencies in a population
(Elsevier Science, 2019-12)
Constant growth of forensic DNA databases requires new STR markers to be developed, tested and validated.Aiming to simplify the process of obtaining allele frequency distributions of new STR loci included in newmegaplexes, ...
A dichotomous key for the discrimination of the already known S-RNase alleles in potato species
(Elsevier, 2014-02)
The potato species exhibit gametophytic self-incompatibility system controlled by a single S-locus withmultiple S-haplotypes. Each S-haplotype carries two genetically linked genes, S-RNase and SLF, controllingthe female ...
A Comprehensive Haplotype Targeting Strategy for Allele-Specific HTT Suppression in Huntington Disease.
(Elsevier, 2019)
Huntington disease (HD) is a fatal neurodegenerative disorder caused by a gain-of-function mutation in HTT. Suppression of mutant HTT has emerged as a leading therapeutic strategy for HD, with allele-selective approaches ...
Effect of allelic variation at the Glu-3 / Gli-1 loci on breadmaking quality parameters in hexaploid wheat [Triticum aestivum L.]
(2015-03)
Low molecular weight glutenin subunits (LMW-GS) encoded by the Glu-3 loci are known to contribute to wheat breadmaking quality. However, the specific effect of individual Glu-3 alleles is not well understood due to their ...
Effect of the Hope FT-B1 Allele on wheat heading time and yield components
(2014-09)
Precise regulation of flowering time is critical for plant reproductive success and, in cereals, to maximize grain yields. Seasonal cues including temperature and day length are integrated to regulate the timing of flowering. ...
Effect of Ahasl1-1 and Ahasl1-4 alleles on herbicide resistance and its associated dominance in sunflower
(John Wiley & Sons Ltd, 2018-09-06)
BACKGROUND: Acetohydroxyacid synthase large subunit 1 (Ahasl1) is a multiallelic locus involved in herbicide resistance in sunflower. Ahasl1-1 and Ahasl1-4 alleles harbor different point mutations that lead to different ...
Allele-specific expression analysis reveals conserved and unique features of preimplantation development in equine ICSI embryos
(Society for the Study of Reproduction, 2021-09)
Embryonic genome activation and dosage compensation are major genetic events in early development. Combined analysis of single embryo RNA-seq data and parental genome sequencing was used to evaluate parental contributions ...