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Artificial pancreas: the Argentine experience
(Argentine Association for the Progress of Science, 2019-12)
The objective of this work is to present a brief review on the international Artificial Pancreas project. In addition, the local project that led to the first Latin American clinical trials with an Artificial Pancreas will ...
Artificial pancreas: Glycemic control strategies for avoiding hypoglycemiaPáncreas artificial: Estrategias de control glucémico que evitan hipoglucemia
(Universidad Nacional de Colombia, 2018-10)
This paper examines the performance of two new closed-loop control strategies developed as part of the Artificial Pancreas project, this being the most promising treatment for type 1 diabetes mellitus. The first strategy ...
Proyecto páncreas artificial en la ArgentinaArtificial Pancreas project in Argentina
(Academia Nacional de Ciencias Exactas, Físicas y Naturales, 2017)
La Diabetes Mellitus Tipo 1 (DMT1) es una enfermedad autoinmune, también llamada diabetes juvenil, que afecta a una gran cantidad de pacientes de todo el mundo. En la República Argentina hay alrededor de 3 millones de ...
Artificial pancreas clinical trials: Moving towards closed-loop control using insulin-on-board constraints
(Elsevier Science, 2018-08)
Artificial pancreas (AP) systems for people with type 1 diabetes (T1DM) combine the use of a smart insulin pump with a Continuous Glucose Monitor (CGM) and a control algorithm to improve the regulation of glycaemia. Based ...
Invalidation and low-order model set for artificial pancreas robust control design
(Elsevier, 2019-04)
The purpose of this work is to compute a linear parameter-varying (LPV) model set that describes the insulin-glucose dynamics in type 1 diabetes (T1D). This set includes a nominal LPV model and dynamic uncertainty and is ...
Artificial pancreas: Evaluating the ARG algorithm without meal announcement
(SAGE Publications Inc., 2019-07)
Background: Either under standard basal-bolus treatment or hybrid closed-loop control, subjects with type 1 diabetes are required to count carbohydrates (CHOs). However, CHO counting is not only burdensome but also prone ...
Linear parameter-varying model to design control laws for an artificial pancreas
(Elsevier, 2018-02)
The contribution of this work is the generation of a control-oriented model for insulin-glucose dynamic regulation in type 1 diabetes mellitus (T1DM). The novelty of this model is that it includes the time-varying nature, ...
Continuous performance monitoring of a closed-loop insulin delivery system using Bayesian Surprise
(QUALIS CAPES (UFSC), 2012-10)
The development of an artificial pancreas for the treatment of insulindependent diabetes is a big challenge for control theory. Many closed-loop algorithms have been widely evaluated for their ability to recreate, as closely ...
Control-Oriented Model with Intra-Patient Variations for an Artificial Pancreas
(Institute of Electrical and Electronics Engineers, 2020-01-27)
In this work, a low-order model designed for glucose regulation in Type 1 Diabetes Mellitus (T1DM) is obtained from the UVA/Padova metabolic simulator. It captures not only the nonlinear behavior of the glucose-insulin ...
Artificial pancreas under stable pulsatile MPC: Improving the closed-loop performance
(Elsevier, 2020-08)
This work presents a pulsatile Zone Model Predictive Control (pZMPC) for the control of blood glucose concentration (BGC) in patients with Type 1 Diabetes Mellitus (T1DM). The main novelties of the algorithm – in contrast ...