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Mode of action on Trypanosoma ad Leishmania spp
(Springer, 2018)
This book addresses chemical and biological aspects related to sesquiterpene lactones (STLs). Experts in different fields have been invited to contribute on this class of compound´s chemistry, isolation and identification, ...
Hedyosulide, a novel trypanosomicidal sesterterpene lactone from Hedyosmum brasiliense Mart. ex Miq
(Elsevier B.V., 2019-10-01)
A new sesterterpene lactone, Hedyosulide, together with five previously described sesquiterpene lactones were isolated from the leaves of Hedyosmum brasiliense Mart. ex Miq. (Chloranthaceae). Their structures were established ...
An unusual dimeric guaianolide with antiprotozoal activity and further sesquiterpene lactones from Eupatorium perfoliatum
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
The CH(2)Cl(2) extract of aerial parts of Eupatorium perfoliatum L. exhibits antiprotozoal activity under in vitro conditions, especially against Plasmodium falciparum (IC(50)=2.7 mu g/ml). The search for active compounds ...
Antiprotozoal activity of dehydrozaluzanin C A sesquiterpene lactone isolated from munnozia maronii (Asteraceae)
(Acta Andina, 1993)
Petroleum ether extract of leaves of Munnozia maronii was found to inhibit in vitro the grouth of promastigote forms of Leishmania and epimastigote forms of Trypanosoma cruzi at a concentration of 25 µg ml-1. Activity ...
Overview
(Springer, 2018)
Sesquiterpene lactones (STLs) are a group of naturally occurringcompounds, most of them found in the Asteraceae family but also present inApiaceae, Magnoliaceae, and Lauraceae. To date about 8000 compounds havebeen reported. ...
Antiprotozoal compounds from Urolepis hecatantha (Asteraceae)
(Hindawi, 2021)
The dewaxed dichloromethane extract of Urolepis hecatantha and the compounds isolated from it were tested for their in vitro activity on Trypanosoma cruzi epimastigotes and Leishmania infantum promastigotes. The extract ...
Antitrypanosomal and antileishmanial activities
(Springer, 2018)
The so-called neglected tropical diseases, which are endemic in 149 tropical and subtropical countries, affect more than 1 billion people annually, including 875 million children in developing economies. These diseases are ...
Antiprotozoal Compounds from Urolepis hecatantha (Asteraceae)
(Hindawi, 2021-02-12)
The dewaxed dichloromethane extract of Urolepis hecatantha and the compounds isolated from it were tested for their in vitro activity on Trypanosoma cruzi epimastigotes and Leishmania infantum promastigotes. The extract ...
Desreplicação dos extratos ativos de Cyrtocymura scorpioides (Asteraceae) contra Candida spp. e Trichomonas vaginalis
(Universidade Estadual Paulista (Unesp), 2020-09-22)
Cyrtocymura scorpioides (Lam.) H. Rob., sinonímia Vernonia scorpioides (Lam) Pers, é uma planta medicinal da América do Sul, sendo utilizada, popularmente, para o tratamento da leucorreia, principal sintoma associado a ...