Antiprotozoal activity of dehydrozaluzanin C A sesquiterpene lactone isolated from munnozia maronii (Asteraceae)

Abstract

Petroleum ether extract of leaves of Munnozia maronii was found to inhibit in vitro the grouth of promastigote forms of Leishmania and epimastigote forms of Trypanosoma cruzi at a concentration of 25 µg ml-1. Activity guided fractionation of the extract by chromatography afforded the sesquiterpene lactone 1 of the guaiane series...