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HLA-G in preeclampsia: a pilot study to propose a tolerogenic treatment
(International Journal of Medical students, 2018)
Cyclosporin A-treated Dendritic Cells may affect the outcome of organ transplantation by decreasing CD4+CD25+ regulatory T cell proliferation
(Sociedad de Biología de Chile, 2010)
One of the mechanisms for generation of tolerance involves immature dendritic cells (DCs) and a subpopulation of regulatory CD4+ CD25+ T lymphocytes (TREG). The purpose of this work was to analyze how Cyclosporine A (CsA), ...
Contribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosus
(Blackwell Publishing Ltd, 2015-12)
Systemic lupus erythematosus (SLE) is a heterogeneous disease in which
excessive inflammation, autoantibodies and complement activation lead to
multisystem tissue damage. The contribution of the individual genetic
composition ...
The demethylase inhibitor GSK-J4 limits inflammatory colitis by promoting de novo synthesis of retinoic acid in dendritic cells
(Nature Research, 2021-12)
Dendritic cells (DCs) promote T-cell mediated tolerance to self-antigens and induce inflammation to innocuous-antigens. This dual potential makes DCs fundamental players in inflammatory disorders. Evidence from inflammatory ...
The demethylase inhibitor GSK-J4 limits inflammatory colitis by promoting de novo synthesis of retinoic acid in dendritic cells
(2021-12)
Dendritic cells (DCs) promote T-cell mediated tolerance to self-antigens and induce inflammation to innocuous-antigens. This dual potential makes DCs fundamental players in inflammatory disorders. Evidence from inflammatory ...
miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence
(PLoS, 2017)
Hepatitis C virus (HCV) requires the liver specific micro-RNA (miRNA), miR-122, to replicate. This was considered unique among RNA viruses until recent discoveries of HCV-related hepaciviruses prompting the question of a ...
Interleukin-10 Production by T and B Cells Is a Key Factor to Promote Systemic Salmonella enterica Serovar Typhimurium Infection in Mice
(Frontiers Media, 2017-08)
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a Gram-negative bacterium that produces disease in numerous hosts. In mice, oral inoculation is followed by intestinal colonization and subsequent systemic ...