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Intracellular signaling pathways involved in childhood acute lymphoblastic leukemia; molecular targets
(Indian Journal of Hematology and Blood Transfusion, 2020)
Epigenetic control and cancer: the potential of histone demethylases as therapeutic targets
(Pharmaceuticals, 2012-06-26)
The development of cancer involves an immense number of factors at the molecular level. These factors are associated principally with alterations in the epigenetic mechanisms that regulate gene expression profiles. Studying ...
Potential Therapeutic Targets in People with Emotional Dependency
(Universidad San Buenaventura, 2019-05-20)
Objective: To examine the relationship between the components of emotional dependency (ED) with anxious, depressive, and impulsive symptomatology. Method: 98 university students (68% women, age M = 20.2 years, ED = 2.19) ...
Drug Target Interaction Prediction Using Machine Learning Techniques – A Review
Drug discovery is a key process, given the rising and ubiquitous demand for medication to stay in good shape right through the course of one’s life. Drugs are small molecules that inhibit or activate the function of a ...
Carbapenem Therapeutic Drug Monitoring in Critically Ill Adult Patients and Clinical Outcomes: A Systematic Review with Meta-Analysis
(Antibiotics, 2021-02-10)
Drug monitoring is one strategy of antibiotic stewardship to face antimicrobial resistance.
This strategy could have a determinant role in critically ill patients treated with carbapenems to
overcome pharmacokinetic ...
Designing and optimizing new antimicrobial peptides: all targets are not the same
Because the resistance of microorganisms to the available antibiotics is a growing healthcare problem worldwide, the search for new antimicrobial peptides (AMPs) that provide useful therapeutic options has been increasing ...