Buscar
Mostrando ítems 1-10 de 286
C677T (RS1801133 ) MTHFR gene polymorphism frequency in a colombian population
(Colombia Médica, 2015)
Introduction:
Abnormal levels of the enzyme methylenetetrahydrofolate reductase (MTHFR) are associated with an increased risk of both cardiovascular and cerebrovascular disease and higher concentrations of homocysteine. ...
Improving furosemide polymorphs properties through supramolecular complexes of beta-cyclodextrin
(2014)
In this work, complexes of β-cyclodextrin and the two solid forms of furosemide were prepared and characterized for their potential pharmaceutical applications, with the interactions between the two compounds being studied ...
Dissolution properties, solid-state transformation and polymorphic crystallization: progesterone case study
(2014)
Progesterone is a natural steroid hormone and a poor soluble drug which presents two polymorphs (forms 1 and 2). Different methods to obtain form 2 were tested and a complete solid-state characterization of both polymorphs ...
Association of tumor necrosis factor alpha-308 promoter polymorphism with spondyloarthritides patients in Colombia
(JCR Journal of Clinical Rheumatology, 2011)
The pathogenesis of SpA is considered to be a
complex and multi-factorial process and, similar to other
autoimmune diseases, includes the activity of proinflammatory
cytokines such as TNF alpha. Our study compared
the -308 ...
Supervised selection of single nucleotide polymorphisms in chronic fatigue syndrome
Introduction: The different ways for selecting single nucleotide polymorphisms have been related to paradoxical conclusions about their usefulness in predicting chronic fatigue syndrome even when using the same dataset. ...