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Produtos naturais como candidatos a fármacos úteis no tratamento do mal de Alzheimer
Alzheimer's disease (AD) is a progressive neurodegenerative pathology with severe economic and social impact. There is currently no cure, although cholinesterase inhibitors provide effective temporary relief of symptoms ...
Analysis of a sub-optimal scheme of drug dosage in the AIDS treatment
Here the results for CD4+T cells count and the viral load obtained from HIV sero-positive patients are compared with results from numerical simulations by computer. Also, the standard scheme of administration of drugs anti ...
Electrochemical determination of antimalarial drug amodiaquine in maternal milk using a hemin-based electrode
Voltammetric analysis of amodiaquine using a hemin biosensor revealed a well-defined peak at 0.14 V (vs. Ag/AgCl), corresponding to the oxidation of amodiaquine at pH 7.0. The electrodic behavior indicated that the oxidation ...
Mathematical analysis and simulations involving chemotherapy and surgery on large human tumours under a suitable cell-kill functional response
Dosage and frequency of treatment schedules are important for successful chemotherapy. However, in this work we argue that cell-kill response and tumoral growth should not be seen as separate and therefore are essential ...