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Human erythrocytes: cytoskeleton and its origin
(Springer, 2020-05)
In the last few years, erythrocytes have emerged as the main determinant of blood rheology. In mammals, these cells are devoid of nuclei and are, therefore, unable to divide. Consequently, all circulating erythrocytes come ...
Nucleus-cytoskeleton communication impacts on OCT4-chromatin interactions in embryonic stem cells
(BioMed Central, 2021-12)
Background: The cytoskeleton is a key component of the system responsible for transmitting mechanical cues from the cellular environment to the nucleus, where they trigger downstream responses. This communication is ...
Abscisic acid and nitric oxide modulate cytoskeleton organization, root hair growth and ectopic hair formation in Arabidopsis
(Academic Press Inc Elsevier Science, 2018-11)
Abscisic acid (ABA) and nitric oxide (NO) are two plant growth regulators that participate in many signaling cascades in different organs all along the plant life. Here, we were interested in deciphering the effects of ABA ...
The role of cytoskeleton and adhesion proteins in the resistance to photodynamic therapy: possible therapeutic interventions
(Royal Society of Chemistry, 2015-04)
It is known that Photodynamic Therapy (PDT) induces changes in the cytoskeleton, the cell shape, and the adhesion properties of tumour cells. In addition, these targets have also been demonstrated to be involved in the ...
Protein tyrosine phosphatase PTP1B in cell adhesion and migration
(Landes Bioscience, 2013-09-12)
Cell migration requires a highly coordinated interplay between specialized plasma membrane adhesion complexes and the cytoskeleton. Protein phosphorylation/dephosphorylation modifications regulate many aspects of the ...
Effects of perinatal asphyxia on rat striatal cytoskeleton
(Wiley-liss, Div John Wiley & Sons Inc, 2012-01)
Perinatal asphyxia (PA) is a medical condition associated with a high short-term morbimortality and different long-term neurological diseases. In previous works, we have shown that neuronal and synaptic changes in rat ...
Differential Effects of G- and F-Actin on the Plasma Membrane Calcium Pump Activity
(Humana Press, 2012-11)
We have previously shown that plasma membrane calcium ATPase (PMCA) pump activity is affected by the membrane protein concentration (Vanagas et al., Biochim Biophys Acta 1768:1641-1644, 2007). The results of this study ...
Small GTPases in plant biotic interactions
(Taylor and Francis, 2017-06-23)
The superfamily of small monomeric GTPases originated in a common ancestor of eukaryotic multicellular organisms and, since then, it has evolved independently in each lineage to cope with the environmental challenges imposed ...
Neuroprotective effects of hypothermia on synaptic actin cytoskeletal changes induced by perinatal asphyxia
(Elsevier Science, 2014-05)
Cerebral hypoxia–ischemia damages synaptic proteins, resulting in cytoskeletal alterations, protein aggregation and neuronal death. In the previous works, we have shown neuronal and synaptic changes in rat neostriatum ...
More than tracks: how the cytoskeleton builds epithelia asymmetry
(Universidad Nacional de La Plata. Facultad de Medicina. Centro de Investigaciones Cardiovasculares. Sociedad Argentina de Fisiología, 2018-04)
Epithelia are three-dimensional arrangements of cells organized into structures which delimit morphologically and physiologically different compartments. At the cellular level, epithelial cells are characterized by the ...