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Calpain translocation and activation as pharmacological targets during myocardial ischemia/reperfusion
(2010)
Calpains contribute to reperfusion-induced myocardial cell death. However, it remains controversial whether its activation occurs during ischemia or reperfusion. We investigated the regulation and time-course of calpain ...
Regulation of cell polarity by controlled proteolytic systems
(SOC BIOLGIA CHILE, 2011)
Epithelial and neuronal cells are highly asymmetric, with discrete regions responsible for different roles that underlie the generation of specific compartments within cells that are distinct in biochemical composition, ...
The Long-Term Impairment in Redox Homeostasis Observed in the Hippocampus of Rats Subjected to Global Perinatal Asphyxia (PA) Implies Changes in Glutathione-Dependent Antioxidant Enzymes and TIGAR-Dependent Shift Towards the Pentose Phosphate Pathways: Ef
(Springer New York LLC, 2019)
We have recently reported that global perinatal asphyxia (PA) induces a regionally sustained increase in oxidized glutathione (GSSG) levels and GSSG/GSH ratio, a decrease in tissue-reducing capacity, a decrease in catalase ...
Down syndrome critical region 1 gene, Rcan1, helps maintain a more fused Mitochondrial Network
(Lippincott Williams & Wilkins, 2018)
Rationale: The regulator of calcineurin 1 (RCAN1) inhibits CN (calcineurin), a Ca2+-activated protein phosphatase important in cardiac remodeling. In humans, RCAN1 is located on chromosome 21 in proximity to the Down ...
Polimorfismos en el gen cast en ovinos del Mato Grosso do Sul, Brasil
(Universidad de Sucre, 2016-01-04)