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Revisão bibliográfica sobre as sínteses da esfingosina, derivados e aplicações biológicas
(Universidade Federal de São Paulo, 2022-06-24)
A Esfingosina ((E)-2-aminooctadec-4-eno-1,3-diol) é um esfingolipídeo sintetizado pela primeira vez em 1954 que compõe a membrana celular e desempenha diversos papéis biológicos importantes, como, por exemplo regulação das ...
Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans
(Elsevier, 2020-01)
How the gut microbiome affects Parkinson's disease remains unclear. Goya et al. show that the probiotic B. subtilis strain PXN21 inhibits and clears α-synuclein aggregation in a C. elegans model. The bacterium acts via ...
Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions
(2020)
Lysosomal storage disorders (LSDs) are diseases characterized by the accumulation of macromolecules in the late endocytic system and are caused by inherited defects in genes that encode mainly lysosomal enzymes or transmembrane ...
Sintese de 2-amino-3, 5-dioisSynthesis of 2-amino-3, 5-diols
([s.n.], 2007)
Follicular Fluid Lipid Fingerprinting From Women With Pcos And Hyper Response During Ivf Treatment
(SPRINGER/PLENUM PUBLISHERSNEW YORK, 2015)
In vivo intrabursal administration of bioactive lipid sphingosine-1-phosphate enhances vascular integrity in a rat model of ovarian hyperstimulation syndrome
(Oxford University Press, 2017-06)
Can the bioactive lipid sphingosine-1 phosphate (S1P) act as an endothelial barrier-enhancing molecule and, in turn, restore the vascular integrity and homeostasis in a rat model of ovarian hyperstimulation syndrome (OHSS). ...
Sphingomyelin composition and physical asymmetries in native acetylcholine receptor-rich membranes
(Springer, 2002-12)
Selective enzymatic hydrolysis, lipid compositional analyses, and fluorescence studies have been carried out on acetylcholine receptor (AChR)-rich membranes from Torpedinidae to investigate the topology of sphingomyelin ...
An efficient procedure for the synthesis of 2-N-Boc-amino-3,5-diols
(Pergamon-elsevier Science LtdOxfordInglaterra, 2008)