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Advances in prodrug design
(2005-10-01)
The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility of polymers and other macromolecules as carriers. PDEPT ...
Advances in prodrug design
(2005-10-01)
The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility of polymers and other macromolecules as carriers. PDEPT ...
Advances in prodrug design
(2014)
Promising inhibitors targeting Mpro: an ideal strategy for anti- SARS-CoV-2 drug discovery
Recently, Dai W et al. published a study on Science,1 in which
the two lead compounds 11a and 11b were designed and
synthesized based on the features of a key enzyme Mpro of SARSCoV-2 (Fig. 1). In particular, compound ...
Renin-angiotensin system as a potential target for new therapeutic approaches in Parkinson’s disease
(Taylor and Francis Ltd, 2017)
Probabilistic Theory of Efficient Internalization of Nanoparticles at Targeted Drug Delivery Strategies
(Institute of Electrical and Electronics EngineersPE, 2020-12-16)
In this paper, the action that lead to an efficiently Targeted Drug Delivery through the process of internalization is studied. Although one can expects that the probability to reach a target is, however in praxis this ...
From Genome to Drugs: New Approaches in Antimicrobial Discovery
(Frontiers Media, 2021)
Major kinds of drug targets in chagas disease or american trypanosomiasis
(Bentham Science Publishers, 2019-08-21)
American Trypanosomiasis, a parasitic infection commonly named Chagas disease, affects millions of people all over Latin American countries. Presently, the World Health Organization (WHO) predicts that the number of ...
Amino acid and polyamine membrane transporters in Trypanosoma cruzi: biological function and evaluation as drug targets
(Bentham Science Publishers, 2019-12)
Amino acids and polyamines are involved in relevant processes for the parasite Trypanosoma cruzi, like protein synthesis, stress resistance, life cycle progression, infection establishment and redox balance, among others. ...