Buscar
Mostrando ítems 31-40 de 275
Jararhagin, a snake venom metalloprotease-disintegrin, activates the Rac1 GTPase and stimulates neurite outgrowth in neuroblastoma cells
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
It has been shown previously that the snake venom metalloprotease-disintegrin jararhagin stimulates cell migration and cytoskeletal rearrangement, independently of its effects on cellular adhesion but possibly associated ...
In vitro cytoskeleton changes of mouse neurons induced by purified HTLV-1, and PBMC from HAM/TSP patients and HTLV-1 carriers
(2004)
HTLV-1 is the causative agent of HAM/TSP. This neurological disease affects the CNS producing damage of the motor tracts at the spinal cord. The HAM/TSP pathogenesis remains undefined. It could include direct and indirect ...
Contribution of NADPH oxidase and the endoplasmic reticulum calcium release in the establishment of hippocampal neuronal polarity and axonal growth
(2015)
Reactive Oxygen Species (ROS) from NADPH (NOX) contribute to LTP, memory
consolidation and neuronal actin cytoskeleton dynamics. Physiological levels of ROS also
promote Ca2+ release from the endoplasmic reticulum (ER). ...
IRE1 controls cytoskeleton remodeling and cell migration as a scaffold that binds Filamin A
(2017)
IRE1α is crucial signal transducer of the unfolded protein response (UPR). Classical activation of IRE1α under
ER stress triggers adaptive and pro-apoptotic signals; however, recent reports have suggested new functions
of ...
Actin cytoskeleton remodelling by sex steroids in neurones
(Wiley Blackwell Publishing, Inc, 2012-01)
Cell morphology and its interaction with the extracellular environment are integrated processes involving a number of intracellular controllers orchestrating cytoskeletal proteins and their interaction with the cell membrane ...
Efectos de la exposición prenatal al agonista cannabinoide WIN55,212-2 sobre la proliferación, la migración y el citoesqueleto neuronal de la rataEffect of prenatal exposure to the cannabinoide receptor agonist WIN55,212-2 on neuronal proliferation, migration and neuronal cytoskeleton in the cerebral cortex of the rat
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2012)
Marlin-1 and conventional kinesin link GABA(B) receptors to the cytoskeleton and regulate receptor transport
(2007)
The cytoskeleton and cytoskeletal motors play a fundamental role in neurotransmitter receptor trafficking, but proteins that link GABA(B) receptors (GABA(B)Rs) to the cytoskeleton have not been described. We recently ...
Automated quantification of protein periodic nanostructures in fluorescence nanoscopy images: Abundance and regularity of neuronal spectrin membrane-associated skeleton
(Nature Publishing Group, 2017-12)
Fluorescence nanoscopy imaging permits the observation of periodic supramolecular protein structures in their natural environment, as well as the unveiling of previously unknown protein periodic structures. Deciphering the ...
TTLL7 and TTLL11 negatively regulate axonal growth and polarity acquisition in mouse hippocampal neurons
(2017)
Microtubules are the largest cytoskeleton filaments and are essential for intracellular transport,
organelle positioning, cell morphology and motility. In cells, the dynamic regulation of the microtubule
network is controlled ...
The protein kinase cdk5: Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology
(2001)
A set of different protein kinases have been involved in tau phosphorylations, including glycogen synthase kinase 3b (GSK3b), MARK kinase, MAP kinase, the cyclin-dependent kinase 5 (Cdk5) system and others. The latter ...