Ponencia
IRE1 controls cytoskeleton remodeling and cell migration as a scaffold that binds Filamin A
Fecha
2017Institución
Resumen
IRE1α is crucial signal transducer of the unfolded protein response (UPR). Classical activation of IRE1α under
ER stress triggers adaptive and pro-apoptotic signals; however, recent reports have suggested new functions
of IRE1α in different physiological