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In vitro and in vivo characterization of anodised zirconium as a potential material for biomedical applications
(Elsevier Science, 2017-02-27)
In vitro studies offer the insights for the understanding of the mechanisms at the tissue–implant interface that will provide an effective functioning in vivo. The good biocompatibility of zirconium makes a good candidate ...
Investigación de un fenómeno natural: ¿estudios in vivo, in vitro o in silico?
(Asociación Argentina de Osteología y Metabolismo Mineral, 2013-12)
Un tema de controversia y discusión en la investigación biomédica es la validez de la información obtenida de los experimentos realizados. Los modelos experimentales utilizados determinan el tipo de conclusiones así como ...
In vitro and in vivo activity of benzo[ c ]phenanthridines against Leishmania amazonensis
(Georg Thieme Verlag, 2014)
Seven benzo[c]phenanthridines, synthetic or isolated from Zanthoxylum rhoifolium root bark, were evaluated against Leishmania amazonensis axenic amastigotes. Five of them were considered leishmanicidal, with IC50 values ...
Recent advances in the use of Galleria mellonella model to study immune responses against human pathogens
(2018-01-01)
The use of invertebrates for in vivo studies in microbiology is well established in the scientific community. Larvae of Galleria mellonella are a widely used model for studying pathogenesis, the efficacy of new antimicrobial ...
Initial Erosion Models
(KargerBaselSuíça, 2011)
In vivo and in vitro models of hepatocellular carcinoma: Current strategies for translational modeling
(2021-11-01)
Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third leading cause of cancer‐related death globally. HCC is a complex multistep disease and usually emerges in the setting of chronic liver ...
In vitro and in vivo activity of voriconazole and benznidazole combination on trypanosoma cruzi infection models
(Elsevier Science, 2020-11)
Combination therapy has been proposed as an ideal strategy to reduce drug toxicity and improve treatment efficacy in Chagas disease. Previously, we demonstrated potent in vivo anti-Trypanosoma cruzi activity of voriconazole. ...