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Role of adenosine in the antiepileptic effects of deep brain stimulation
(Frontiers Research Foundation, 2014-10-02)
Despite the effectiveness of anterior thalamic nucleus (AN) deep brain stimulation (DBS) for the treatment of epilepsy, mechanisms responsible for the antiepileptic effects of this therapy remain elusive. As adenosine ...
Deep Brain Stimulation in the Posteromedial Hypothalamic Nuclei in Refractory Aggressiveness: Post-Surgical Results of 19 Cases
(Cambridge University Press, 2021-12-08)
Aggression is a clinical manifestation that usually occurs in neurodevelopmental disorders. In intellectual disability, dysfunctional behavior and aggressive and maladaptive responses are common. These facts put at risk ...
Long-Term Effects of Anterior Thalamic Nucleus Deep Brain Stimulation on Spatial Learning in the Pilocarpine Model of Temporal Lobe Epilepsy
(Wiley, 2018)
Introduction and ObjectivesCognitive impairment is a significant comorbidity of temporal lobe epilepsy that is associated with extensive hippocampal cell loss. Deep brain stimulation (DBS) of the anterior thalamic nucleus ...
Implantable pulse generators for deep brain stimulation: challenges, complications, and strategies for practicality and longevity
(Frontiers Media, 2021)
Deep brain stimulation (DBS) represents an important treatment modality for movement disorders and other circuitopathies. Despite their miniaturization and increasing sophistication, DBS systems share a common set of ...
Bilateral subthalamic nucleus stimulation for generalized dystonia after bilateral pallidotomy
(WILEY-BLACKWELLHOBOKEN, 2012)
Background: Thalamotomies and pallidotomies were commonly performed before the deep brain stimulation (DBS) era. Although ablative procedures can lead to significant dystonia improvement, longer periods of analysis reveal ...
c-FOS Expression After Hippocampal Deep Brain Stimulation in Normal Rats
(Wiley-Blackwell, 2014-04-01)
ObjectivesWe studied the effects of Hip-deep brain stimulation (DBS) on the expression of the inducible transcription factor c-FOS in the brain of normal rats.Materials and MethodsTen Wistar rats were anesthetized, and ...
Subthalamic deep brain stimulation modulates small fiber-dependent sensory thresholds in Parkinson's disease
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
The effects of deep brain stimulation of the subthalamic nucleus on nonmotor symptoms of Parkinson's disease (PD) rarely have been investigated. Among these, sensory disturbances, including chronic pain (CP), are frequent ...
Asymmetrical Contribution of Brain Structures to Treatment-Resistant Depression As Illustrated by Effects of Right Subgenual Cingulum Stimulation
(American Psychiatric Publishing, Inc, 2010-08)
Major depressive disorder is one of the most common psychiatric disorders, with a worldwide lifetime prevalence rate of 10%-20% in women and a slightly lower rate in men. While many patients are successfully treated using ...
Estimulación cerebral profunda en enfermedad de Parkinson
(2018)
Background: Deep brain stimulation is an essential therapeutic tool in Parkinson´s disease. Aim: To assess the results of a series of patients with Parkinson’s
disease treated with micro-electrode guided subthalamic nucleus ...