info:eu-repo/semantics/article
Asymmetrical Contribution of Brain Structures to Treatment-Resistant Depression As Illustrated by Effects of Right Subgenual Cingulum Stimulation
Fecha
2010-08Registro en:
Guinjoan, Salvador Martín; Mayberg, Helen S.; Costanzo, Elsa Y.; Fahrer, Rodolfo D.; Tenca, Eduardo; et al.; Asymmetrical Contribution of Brain Structures to Treatment-Resistant Depression As Illustrated by Effects of Right Subgenual Cingulum Stimulation; American Psychiatric Publishing, Inc; Journal of Neuropsychiatry and Clinical Neurosciences; 22; 3; 8-2010; 265-277
0895-0172
1545-7222
Autor
Guinjoan, Salvador Martín
Mayberg, Helen S.
Costanzo, Elsa Y.
Fahrer, Rodolfo D.
Tenca, Eduardo
Antico, Julio
Cerquetti, Daniel
Smyth, Elisa
Leiguarda, Ramón Carlos
Nemeroff, Charles B.
Resumen
Major depressive disorder is one of the most common psychiatric disorders, with a worldwide lifetime prevalence rate of 10%-20% in women and a slightly lower rate in men. While many patients are successfully treated using established therapeutic strategies, a significant percentage of patients fail to respond. This report describes the successful recovery of a previously treatment-resistant patient following right unilateral deep brain stimulation of Brodmann´s area 25. Current therapeutic approaches to treatment-resistant patients are reviewed in the context of this case with an emphasis on the role of the right and left hemispheres in mediating disease pathogenesis and clinical recovery.