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Cloning and expression of transgenes using linear vectors in Trypanosoma cruzi
(Elsevier, 2014-04)
The identification of new targets for vaccine and drug development for the treatment of Chagas’ disease is dependent on deepening our understanding of the parasite genome. Vectors for genetic manipulation in Trypanosoma ...
Heterologous expression of a Trypanosoma cruzi surface glycoprotein (gp82) in mammalian cells indicates the existence of different signal sequence requirements and processing
(Soc Protozoologists, 1999-11-01)
Metacyclic trypomastigotes of Trypanosoma cruzi express a developmentally regulated 82 kDa surface glycoprotein (gp82) that has been implicated in the mammalian cell invasion. When the non-infective epimastigote stage of ...
Avaliação da função da Interleucina 32γ humana (IL-32γ) durante as infecções aguda e crônica da toxoplasmose em camundongos transgênicosEffects of human Interleukin 32γ (IL-32γ) in transgenic mice during acute and chronic infection of Toxoplasma gondii
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Imunologia e Parasitologia Aplicadas, 2019)
A flow cytometer-based method to simultaneously assess activity and selectivity of compounds against the intracellular forms of Trypanosoma cruzi
(Elsevier Science, 2015-12-10)
Chagas disease is a major unsolved health issue in Latin America and an emerging threat worldwide. New drugs are urgently needed for chemotherapy as those available (benznidazole and nifurtimox) have variable efficacy and ...
Laboratory techniques to obtain different forms of Trypanosoma cruzi: applications to wild-type and genetically modified parasites
(Folia Parasitologica, 2013-03)
Nowadays, there are no simple techniques for mimicking in vitro the life cycle of the kinetoplasmtid Trypanosoma cruzi Chagas, 1909, causative agent of Chagas disease, especially for parasite strains maintained as epimastigotes ...
Parasitismo natural de ovos do curuquerê-do-algodoeiro por trichogramma pretiosum (hymenoptera: Trichogrammatidae) em diferentes estágios fenológicos de variedades de algodoeiros em ipameri, go
(2010-03-01)
The cotton can be damaged by many pests, standing out among them cotton leafworm, responsible for major losses in production, if not controlled properly. A group of natural enemies is the most studied of the family ...
Efeitos do pólen de algodão Bt (Cry1Ac + cry1f) em algumas características biológicas de Trichogramma pretiosum Riley, 1879 (Hymenoptera: Trichogrammatidae)Effects of Bt cotton pollen (Cry1Ac + Cry1F) on some biological characteristics of Trichogramma pretiosum Riley, 1879 (Hymenoptera: Trichogrammatidae)
(Universidade Federal da Grande DouradosBrasilFaculdade de Ciências Biológicas e AmbientaisPrograma de pós-graduação em Entomologia e Conservação da BiodiversidadeUFGD, 2019)
Anti-parasitic effect of vitamin C alone and in combination with benznidazole against Trypanosoma cruzi
(Public Library of Science, 2018-09)
Background: Drugs currently used for the treatment of Chagas’ disease, nifurtimox and benznidazole, have a limited effectiveness and toxic side effects. With the aim of finding new therapeutic approaches, in vitro and in ...