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Mostrando ítems 11-20 de 117
Caracterização de genes de Trypanosoma cruzi envolvidos na via de biossíntese de glicosilfosfatidilinositol
(Universidade Federal de Minas GeraisUFMG, 2013-08-26)
Glycosylphosphatidylinositol (GPI) is the predominant structure that Trypanosoma cruzi uses to anchor proteins on its surface, many of them essential for the virulence of the parasite or its escape from the host immune ...
Signaling triggered by Thy-1 interaction with β3 integrin on astrocytes is an essential step towards unraveling neuronal Thy-1 function
(2002)
Thy-1 is an abundant neuronal glycoprotein in mammals. Despite such prevalence, Thy-1 function remains largely obscure in the absence of a defined ligand. Recently described evidence that Thy-1 interacts with β3 integrin ...
Signaling triggered by Thy-1 interaction with ß3 integrin on astrocytes is an essential step towards unraveling neuronal Thy-1 function
(Sociedad de Biología de Chile, 2002)
Cholesterol depletion induces PKA-mediated basolateral-to-apical transcytosis of the scavenger receptor class B type I in MDCK cells
(NATL ACAD SCIENCES, 2004)
Cholesterol-based membrane microdomains, or lipid rafts, are believed to play important, yet poorly defined, roles in protein trafficking and signal transduction. In polarized epithelial cells, the current view is that ...
GPIomics: global analysis of glycosylphosphatidylinositol-anchored molecules of Trypanosoma cruzi
(NATURE PUBLISHING GROUP, 2009)
Glycosylphosphatidylinositol (GPI) anchoring is a common, relevant posttranslational modification of eukaryotic surface proteins. Here, we developed a fast, simple, and highly sensitive (high attomole-low femtomole range) ...
Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway
(Elsevier B.V., 2017)
© 2016 Elsevier B.V. Two key proteins for cellular communication between astrocytes and neurons are αvβ3 integrin and the receptor Thy-1. Binding of these molecules in the same (cis) or on adjacent (trans) cellular membranes ...
Identification of complete precursors for the glycosylphosphatidylinositol protein anchors of Trypanosoma cruzi
(Amer Soc Biochemistry Molecular Biology Inc, 1996-07-12)
The survival of Trypanosoma cruzi, the causative agent of Chagas' disease, depends vitally on proteins and glycoconjugates that mediate the parasite/host interaction. Since most of these molecules are attached to the ...