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Mostrando ítems 11-20 de 153
Metabolic Imbalance Effect on Retinal Müller Glial Cells Reprogramming Capacity: Involvement of Histone Deacetylase SIRT6
(Frontiers Media, 2021-11)
Retinal Müller glial cells (MGs) are among the first to demonstrate metabolic changes during retinal disease and are a potential source of regenerative cells. In response to a harmful stimulus, they can dedifferentiate ...
Reprogramação de células astrogliais em neurônios utilizando pequenas moléculas orgânicas
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM NEUROCIÊNCIAS, 2018-11-28)
The reprogramming of different specialized cell types into others has been widely studied
in recent years. More specifically, the generation of induced neurons (iNs) from other
differentiated cells is applied to study ...
Pluripotent Reprogramming of Fibroblasts by Lentiviralmediated Insertion of SOX2, C-MYC, and TCL-1A
(MARY ANN LIEBERT INC, 2011)
Reprogramming of somatic cells to pluripotency promises to boost cellular therapy. Most instances of direct reprogramming have been achieved by forced expression of defined exogenous factors using multiple viral vectors. ...
Geração de células semelhantes a hepatócitos por reprogramação direta de células-tronco mesenquimais
(Instituto Gonçalo Moniz, 2019)
Directly reprogrammed human neurons to understand age-related energy metabolism impairment and mitochondrial dysfunction in healthy aging and neurodegeneration
(Hindawi, 2021)
Brain aging is characterized by several molecular and cellular changes grouped as the hallmarks or pillars of aging, including
organelle dysfunction, metabolic and nutrition-sensor changes, stem cell attrition, and ...
Reprogramming the tumor metastasis cascade by targeting galectin-driven networks
(Portland Press, 2021-02)
A sequence of interconnected events known as the metastatic cascade promotes tumor progression by regulating cellular and molecular interactions between tumor, stromal, endothelial, and immune cells both locally and ...