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On the role of mining exposure in epigenetic effects in parkinson’s disease
(Springer, 2017)
To explore the possible influence of heavy metal
mining on incidence of Parkinson’s disease (PD), global
DNA methylation was assessed in blood samples from a population
of PD patients (n = 45) and control subjects (n = ...
Epigenetic pathways regulating bone homeostasis:Potential targeting for intervention of skeletal disorders
(Current Medicine Group LLC 1, 2014)
Epigenetic regulation utilizes different mechanisms to convey heritable traits to progeny cells that are independent of DNA sequence, including DNA silencing, posttranslational modifications of histone proteins, and the ...
Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas
(Springer, 2010-05-04)
Most breast carcinomas that are estrogen receptor (ER) and progesterone receptor (PR) positive respond initially to an endocrine therapy, but over time, they develop resistance (acquired hormone resistance). Others, however, ...
Polyphenols and iugr pregnancies: effects of maternal hydroxytyrosol supplementation on placental gene expression and fetal antioxidant status, dna-methylation and phenotype
(2019)
The use of polyphenols is a promising strategy for preventing or alleviating intrauterine growth restriction (IUGR) because polyphenol supplementation increases plasma antioxidant capacity and improves oxidative stress at ...
Engram formation in psychiatric disorders
(Frontiers Research Foundation, 2014)
Environmental factors substantially influence beginning and progression of mental illness, reinforcing or reducing the consequences of genetic vulnerability. Often initiated by early traumatic events, "engrams" or memories ...
Automated generation of context-specific gene regulatory networks with a weighted approach in Drosophila melanogaster
(Royal Soc, England, 2021)
The regulation of gene expression is a key factor in the development and maintenance of life in all organisms. Even so, little is known at whole genome scale for most genes and contexts.We propose a method, Tool forWeighted ...
MethylMix 2.0: An R package for identifying DNA methylation genes
(Oxford University Press, 2018-09)
Summary: DNA methylation is an important mechanism regulating gene transcription, and its role in carcinogenesis has been extensively studied. Hyper and hypomethylation of genes is a major mechanism of gene expression ...
Fruit quality and DNA methylation are affected by parental order in reciprocal crosses of tomato
(Springer, 2020-10)
Crosses between different genotypes and even between different species arecommonly used in plant breeding programs. Reciprocal hybrids are obtained bychanging the cross direction (or the sexual role) of parental genotypes ...